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Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part I

Not Applicable
Completed
Conditions
Core Temperature
Heat Stress, Exertional
Exercise
Heat Fatigue
Interventions
Other: Simulated work in the heat
Registration Number
NCT05847712
Lead Sponsor
University of Ottawa
Brief Summary

Workplaces rely on upper heat stress limits provided by the American Conference of Governmental Industrial Hygienists (ACGIH) to manage the health and safety of workers in hot environments. This is primarily achieved by interspersing work with rest periods, the length of which is dictated by environmental conditions and work intensity, to maintain core temperature at or below 38.0°C (equivalent to a 1°C increase in body core temperature above resting levels). However, these guidelines employ a "one size fits all" approach to exposure limits that does not consider individual variation between workers. Moreover, they fail to provide direction on the safe, initial stay times before these heat-mitigation controls should be employed (i.e., rest breaks) in conditions exceeding upper heat stress limits. While recent work has generated estimates of the initial stay times for young to older men before heat-mitigation controls are required for moderate-intensity work, this information is limited to a single work bout and does not consider a second work bout preceded by an extended rest period (e.g., lunch) or next day effects. This is a key consideration, as prolonged work in the heat has been shown to cause next-day impairments in heat dissipation in older men. Further, it remains unclear if the application of the prescribed ACGIH work-rest allocations thereafter would alleviate increases in core temperature for the duration of the work period (e.g., start of shift versus post-lunch period). This project will address these knowledge gaps by determining if refinements in initial stay times for moderate-intensity work (represents the average work effort of physically demanding occupations) in the heat (26°C wet-bulb globe temperature) may be required for young and older adults for i) a second work bout that is preceded by an extended rest period such as a lunch break, and ii) a work bout performed on the next day. This includes assessing the efficacy of the prescribed ACGIH work-rest allocations to mitigate increases in core temperature beyond safe limits (\>38.0°C, equivalent to a \>1°C increase in body core temperature above resting levels) during these work periods. Given the known sex-differences in heat loss that can modulate core temperature regulation during an exercise-heat stress, the investigators will conduct separate analysis to identify modulating effects of biological sex on the initial stay times and effectiveness of the work-rest allocation as a heat-alleviation control.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • young (18-30 years) and older adults (50-69 years)
  • habitually active, not endurance trained (<2 sessions per week, <150 minutes per week)
  • non-smoking
  • English or French speaking
  • ability to provide informed consent
Exclusion Criteria
  • pre-existing health conditions (e.g., diabetes, hypertension)
  • use of medication deemed to significantly modulate thermoregulatory function and heat tolerance (e.g., antidepressants, antihistamines, diuretics)
  • engaged in jobs and/or activities that involve frequent exposure to hot environments (e.g., regular sauna use)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Older adultsSimulated work in the heatAdults aged 50-69 with no pre-existing health conditions
Younger adultsSimulated work in the heatAdults aged 18-30 years with no pre-existing health conditions
Primary Outcome Measures
NameTimeMethod
Initial stay timeEnd of third (morning day 2) continuous work bout

Total continuous work time to achieve an initial absolute increase in core temperature of 38°C (equivalent to a 1°C increase in body core temperature above resting levels) (note: in instances where a participant voluntarily terminates work prematurely before the absolute core temperature of ≥38°C (or relative increase of ≥1°C) is achieved or the absolute core temperature is \<38°C (or relative increase of \<1°C), the time of termination or end of the work bout will be taken as the initial stay time respectively).

Average core temperaturePeriod of work-rest allocations following initial stay time for morning day 2

Average core temperature following initial stay time

Secondary Outcome Measures
NameTimeMethod
Average skin temperaturePeriod of work-rest allocations following initial stay time for morning day 2

Average skin temperatures following initial stay time

Skin temperature at initial stay timeEnd of third (morning day 2) continuous work bout

Skin temperature (4 sites) measured at the initial increase in absolute core temperature of 38°C (or relative increase of 1°C)

Systolic blood pressureEnd of third (morning day 2) work period

Arterial blood pressure measured via automated oscillometry

Rate pressure productEnd of third (morning day 2) work period

Calculated as systolic blood pressure \* heart rate

Orthostatic Intolerance Symptoms AssessmentPeriod of work-rest allocations following initial stay time for morning day 2

Cumulative sum of scores on 6 questions asking participant to rank symptoms associated with orthostatic intolerance. All symptoms scored on a scale from 0 (none) to 10 (worst possible) and include feelings of: (1) "dizziness, lightheadedness, feeling faint, or feeling like you might black out"; (2) "Problems with vision (blurring, seeing spots, tunnel vision, etc.)"; (3) "Weakness"; (4) "Fatigue"; (5) "Trouble concentrating"; and (6) "Head and neck discomfort".

Heart rate at initial stay timeEnd of third (morning day 2) continuous work bout

Heart rate at the initial increase in absolute core temperature of 38°C (or relative increase of 1°C)

Fluid lossEnd of third (morning day 2) work period

Fluid loss calculated as the change in body mass (corrected for food/fluid consumption).

Change in plasma volumeEnd of third (morning day 2) work period

Determined from venous blood samples

Thirst sensation scalePeriod of work-rest allocations following initial stay time for morning day 2

Assessed via a visual analog scale ("How thirsty are you?") (9: very, very thirsty to 1: Not thirsty at all)

Average heart ratePeriod of work-rest allocations following initial stay time for morning day 2

Average heart rate following initial stay time

Diastolic blood pressureEnd of third (morning day 2) work period

Arterial blood pressure measured via automated oscillometry

Mean arterial blood pressureEnd of third (morning day 2) work period

Calculated as 1/3 \* systolic blood pressure + 2/3 \* diastolic blood pressure

Fluid consumptionEnd of third (morning day 2) work period

Cumulative fluid consumption calculated by weighing the participant's water intake

Rating of Perceived ExertionPeriod of work-rest allocations following initial stay time for morning day 2

Perceived exertion assessed via a self-report questionnaire upon verbal prompting (6: no exertion at all to 20: maximal exertion).

Thermal comfort scalePeriod of work-rest allocations following initial stay time for morning day 2

Thermal comfort assessed via a visual analog scale ("How comfortable does your body temperature feel?") (4: very uncomfortable to 1: comfortable)

Trial Locations

Locations (1)

University of Ottawa

🇨🇦

Ottawa, Ontario, Canada

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