Food Intake and Epigenetic Alteration in the Spermatozoa of Singletons and Twins (FEASST) Study: An Australian partner study conducted in male twins

Not Applicable

• Conditions: obesity; Depression; anxiety; subfertility; Diet and Nutrition - Obesity; Mental Health - Anxiety; Mental Health - Depression; Reproductive Health and Childbirth - Fertility including in vitro fertilisation; Reproductive Health and Childbirth - Other reproductive health and childbirth disorders

• Registration Number: ACTRN12623000194662
• Lead Sponsor: ovo Nordisk Foundation

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-02-23
• Last Update Posted: 6 March 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Male
• Target Recruitment: 50

Inclusion Criteria

Male monozygotic twin
Male dizygotic twin
Age 18-45 years old
No disease of the reproductive system
Non-smoker
Normal semen parameters (volume, concentration, motility) according to WHO's criteria for semen quality
Healthy weight range (BMI 18.5-30)
Fluent in English
Normal liver and renal function

Exclusion Criteria

Self-reported history of serious or chronic illness
Self-reported history of obesity
History of food restrictions, allergies, and/or disordered eating
Currently actively trying to conceive a child
Diagnosis of infertility or disease of the reproductive system
Evidence of dysregulated metabolism, characterized by the occurrence of any one of the following:
oWaist circumference >102 cm
oBlood pressure > 130/85 mm Hg

Study & Design

• Study Type: Interventional
• Study Design: Not specified