Evaluation of the effectiveness of Coix lacrymae and different concoctions in people with eczema caused by spleen deficiency and dampness
- Conditions
- Spleen deficiency and dampness type eczema
- Registration Number
- ITMCTR2023000048
- Lead Sponsor
- Affiliated Hospital of Jiangxi University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1) Age 18 to 65 years old, regardless of gender;
2) Those diagnosed with eczema of the spleen deficiency and dampness type;
3) Those who have not participated in other clinical studies within 3 months;
4) Those who voluntarily participated in this project with follow-up after adequate communication and signed the informed consent form.
1) combined with serious primary diseases of the heart, brain and hematopoietic system, combined with serious liver and kidney function impairment, with malignant tumors, etc;
2) in the preparation period, pregnancy or breastfeeding period
(3) Combined with a major mental illness and unable or unwilling to cooperate
4) Known hypersensitivity to the components of this test article;
5) Those who have used Chinese medicine or proprietary Chinese medicine with similar efficacy to Coix Seed and different concoctions in the last 2 weeks, which affects the judgment of the results.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ATP;Eczema Area and Severity of Involvement Scale (EASI) scale;AQP3;Pruritus level (VAS) scale;Chinese Medicine Evidence Scale;phospho-p38 MAPK,p38MAPK;
- Secondary Outcome Measures
Name Time Method Trans Epidermal Water Loss, TEWL;Skin Barrier Test;Dermatology Quality of Life Index (DLQI) Scale;Skin surface pH;eosinophil;neutrophil;stratum corneum hydration,SCH;Sebum content;