NCT03662724招募中不适用
Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Course in the Treatment of Acute Myeloid Leukemia With Venetoclax: The Venetoclax Registry
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Overall response rate of Venetoclax treatment.
研究概览
简要总结
Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Course in the Treatment of Acute Myeloid Leukemia With Venetoclax
详细描述
The aim of this study is to document all patients with AML who are treated with the BCL2 inhibitor Venetoclax outside a clinical trial in all hospitals participating in this registry study in a standardised manner. Data is collected retrospectively and multi-centric. It is neither a therapy study nor is the therapy influenced by this study.
- Systematic and uniform collection and documentation of all patients treated with the BCL2 inhibitor Venetoclax.
- Collection and integrative analysis of clinical data of included patients.
- Mutation analysis of available patient samples and correlation with clinical parameters.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 16 Years 至 —(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •relapsed/refractory AML
排除标准
- 未提供
结局指标
主要结局
Overall response rate of Venetoclax treatment.
时间窗: 4 months
Overall response rate of Venetoclax treatment (complete remission, complete remission with incomplete regeneration, partial remission)
次要结局
- Overall survival during Venetoclax treatment(5 years)
- Event-free survival during Venetoclax treatment(5 years)
- Relapse-free survival during Venetoclax treatment(5 years)
研究者
研究点 (1)
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