NCT03535519Unknown不适用
Rheumatoid Arthritis Ultrasound Response to Methotrexate
Juan Carlos Nieto1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2018年8月7日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Ultrasound response
研究概览
简要总结
Observational and prospective study of the ultrasound response to methotrexate in rheumatoid arthritis patients who started methotrexate
详细描述
- Rheumatoid arthritis patients with active disease who start subcutaneous methotrexate by their rheumatologist prescription methotrexate will be included.
- Patients will participate in a prospective and observational study in which the response to methotrexate will be assessed by ultrasound (US) of joints and tendons.
- The main objective of the study is the change in B mode and Doppler mode US after 24 weeks of methotrexate treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Active rheumatoid arthritis fulfilling EULAR criteria.
- •Prescription of methotrexate by a rheumatologist.
- •Informed consent signed by the patient.
排除标准
- 未提供
结局指标
主要结局
Ultrasound response
时间窗: Basal and at 6 months
Change in B mode and Doppler mode synovitis and tenosynovitis
次要结局
- Clinical response(Basal and 6 months)
- Functional response(Basal and 6 months)
研究者
Juan Carlos Nieto
Principal investigator
Hospital General Universitario Gregorio Marañon
研究点 (1)
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