Randomised phase II trial comparing intensive induction chemotherapy (CBOP BEP) with standard BEP chemotherapy in poor prognosis male germ cell tumours

Phase 2

Completed

• Conditions: Male non-seminoma germ cell tumours (NSGCT); Cancer; Testicular cancer

• Registration Number: ISRCTN53643604
• Lead Sponsor: Medical Research Council (MRC) (UK)

Brief Summary

2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/25001888 results 2020 Results article in https://www.ncbi.nlm.nih.gov/pubmed/32007714 results (added 03/02/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2004-10-22
• Study Completion: 2010-06-01
• Last Update Posted: 7 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 89

Inclusion Criteria

1. Non-seminomatous germ cell tumour of any extracranial primary site
2. Poor prognosis features, as defined by the International Germ Cell Cancer Collaborative Group (IGCCCG) criteria
3. Performance status 0 - 3
4. Globular filtration rate greater than 50 ml/min
5. No comorbid condition

Exclusion Criteria

Not provided at time of registration

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ot provided at time of registration

Secondary Outcome Measures

Name	Time	Method
ot provided at time of registration