Safety and Efficacy of Dinoprostone (Propess) in the Women With Premature Rupture of Membrane or Gestational Age <38
Phase 2
Completed
- Conditions
- Induction of Labor
- Interventions
- Drug: Propess insertion group
- Registration Number
- NCT01916291
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Dinoprostone(propess) is commonly used for induction of labor in the pregnant women who has intact membrane after 38weeks of gestational age. The investigators study safety and efficacy of dinoprostone in the pregnant women with premature rupture of membrane or GA\<38weeks
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 189
Inclusion Criteria
- Pregnant women who admitted for induction of labor
- Bishop score <= 6
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Exclusion Criteria
- Contraindication to induction of labor
- Active labor
- Vaginal bleeding, unknown origin
- Hypersensitive to Prostaglandin E
- History of asthma, glaucoma
- Infection (birth canal)
- Placental abruption
- Multiparity(>5)
- Pelvic inflammatory disease
- Heart, lung, kidney disease
- Multiple pregnancy
- Major anomaly
- Fetal distress before induction of labor
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Propess insertion Propess insertion group -
- Primary Outcome Measures
Name Time Method Induction success rate after propess insertion Day 1 after propess insertion
- Secondary Outcome Measures
Name Time Method Concentration of prostaglandinE at delivery
Trial Locations
- Locations (2)
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of
Seoul Metropolitan Goverment Seoul National University Boramae Medical Center
🇰🇷Seoul, Korea, Republic of