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Clinical Trials/NCT02454894
NCT02454894
Withdrawn
Not Applicable

Optimization Lumbar Puncture In Children

Beijing Children's Hospital0 sitesMay 2015

Overview

Phase
Not Applicable
Intervention
postoperative management
Conditions
Spinal Puncture Complications
Sponsor
Beijing Children's Hospital
Primary Endpoint
Number of participants with Postoperation complications include headache, backache, vomit, cerebral hernia, allergy
Status
Withdrawn
Last Updated
10 years ago

Overview

Brief Summary

The study is carried out in a prospective randomized controlled way. In the context of informed understanding from parents, compared with traditional process(no anesthesia; lying without the pillow and fasting water and food for four hours after lumbar puncture), randomly select lidocaine surface anesthesia and postoperative management (lying without the pillow for half an hour after lumbar puncture) . All children will be evaluated by the FLACC(The face,legs,activity,cry,consolability behavioral tool) scale to assess the degree of pain during and after lumbar puncture. Lumber puncture time, success rate and any postoperative condition will be recorded and analyzed.A questionaire about the operation for all parents and children will be investigated in order to establish an optimized lumbar puncture management process.

Detailed Description

The purpose of this study is to establish an optimized lumbar puncture management process on the basis of fully understanding of parents and children. An improved process consisting of painless lumbar puncture (LP),less postoperative complications and comfortable LP will be anticipated.

Registry
clinicaltrials.gov
Start Date
May 2015
End Date
March 2016
Last Updated
10 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Sponsor
Beijing Children's Hospital
Responsible Party
Principal Investigator
Principal Investigator

Gang Liu

Chief physician/Professor

Beijing Children's Hospital

Eligibility Criteria

Inclusion Criteria

  • children with indications of lumbar puncture;
  • voluntarily signed the informed consent

Exclusion Criteria

  • topical anesthetic skin allergies;
  • skin infection in lumbar puncture site;
  • severe intracranial hypertension;
  • unstable vital signs;
  • coagulopathy;
  • intracranial hemorrhage and occupying;
  • low back pain;
  • headache and low back pain before lumbar puncture;
  • past headache after lumbar puncture;
  • mental retardation, neuropsychiatric symptoms;

Arms & Interventions

Group 1

no anesthesia; postoperative management

Intervention: postoperative management

Group 3

surface anesthesia with lidocaine; postoperative management

Intervention: lidocaine

Group 3

surface anesthesia with lidocaine; postoperative management

Intervention: postoperative management

Group 4

surface anesthesia with lidocaine; lying without the pillow and fasting water and food for four hours after lumbar puncture

Intervention: lidocaine

Outcomes

Primary Outcomes

Number of participants with Postoperation complications include headache, backache, vomit, cerebral hernia, allergy

Time Frame: up to five days postoperation

Secondary Outcomes

  • time of lumbar puncture(intraoperative)
  • degree of adaptability(intraoperative)
  • comfort degree(up to four hours postoperation)
  • Composite measure of Vital signs include heart rate, pulse, blood pressure and respiration.(up to four hours postoperation)
  • number of puncture(intraoperative)
  • success rate(intraoperative)
  • whether bad memories exist or not(up to four hours postoperation)

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