A new management method for propofol intravenous sedation using a target-controlled infusion (TCI) pump -The investigation of the optimal initial target blood concentration value in resetting strategy for the target blood concentration at optimal sedation level
Not Applicable
- Conditions
- Mainly impacted teeth
- Registration Number
- JPRN-UMIN000017197
- Lead Sponsor
- Hokkaido University Hospital
- Brief Summary
The higher initial target blood concentration was set from 2.2mcg.ml, the shorter induction time was. However, Maximum difference between the brain concentration at each point during surgery was larger. That is, the most advantage of this method became impaired. Therefore, optimal initial blood concentration seemed to be 2.2mcg.ml in this method.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
habitual user of tranquilizer patient with liver or renal dysfunction obesity patient who's body mass index was more than 30%
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)Maximum difference between the brain concentration at optimal sedation during induction and the target blood concentration at each point during surgery 2)The duration till optimal sedation was achieved
- Secondary Outcome Measures
Name Time Method 1)SPO2, blood pressure 2)Brain concentration at optimal sedation during induction