Feasibility of a Benzodiazepine Deprescribing Intervention in Older Adults Living in the Belgian Community Setting
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Pharmacists' adherence to the intervention
研究概览
简要总结
The goal of this feasibility study is to evaluate the feasibility of an intervention, led by the pharmacist, aiming at benzodiazepines and z-drugs deprescribing in older adults living in the Belgian community setting. The main questions it aims to answer are:
- To what extent will Belgian community pharmacists adhere to the intervention?
- To what extent will patients and general practitioners take up the intervention to deprescribe benzodiazepines and z-drugs?
- To what extent is the design of the recruitment and data collection process feasible and acceptable for all participants?
Participants will receive an educational brochure from their pharmacist. Their pharmacist will also propose to send a new standardized form to their general practitioner to enhance collaboration about a potential benzodiazepine deprescribing.
Researchers will compare this intervention to usual care to see if the intervention is feasible and to gather first data on intervention effectiveness in benzodiazepine deprescribing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •being aged ≥65 years,
- •taking a benzodiazepine receptor agonist for ≥4 weeks (Anatomical Therapeutic Chemical codes: N05BA, N05CD, N05CF and N03AE01)
- •being a regular patient of the community pharmacy (defined as ≥ 4 visits/12 previous months).
排除标准
- •Severe mental illness (assessed through having an active prescription of any antipsychotic medication).
- •Dementia or significant cognitive impairment (assessed through an active prescription or any past prescription during the last 12 months of anticholinesterase inhibitors or memantine) and/or pharmacist's judgment).
- •Patients unable to read or communicate in French.
- •Ongoing benzodiazepine receptor agonist withdrawal at the time of recruitment.
- •Known current alcohol withdrawal.
结局指标
主要结局
Pharmacists' adherence to the intervention
时间窗: At 6 months
Has the intervention been implemented as intended? (e.g: global number of implemented intervention components)
Feasibility of the data collection process
时间窗: At 6 months
The feasibility of the data collection process will be assessed through the quality of the collected data (rate of missing data).
Participants' responsiveness
时间窗: At 6 months
How far participants (pharmacists, patients, and general practitioners) have responded to the intervention and have been engaged by the intervention: e.g. number of altered prescriptions).
Feasibility of the recruitment process
时间窗: At 6 months
The feasibility of the recruitment will be assessed (e.g. the ratio between the number of included patients and patients contacted for participation).
次要结局
- Mechanisms of impact potentially influencing the intervention(At 6 months)
- Contextual factors potentially influencing the intervention effects at the patient-level.(At baseline)
- Contextual factors potentially influencing the intervention effects at the pharmacist-level.(At baseline)
- Exploratory benzodiazepine deprescribing rate analysis(At 6 months)