Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery

Not Applicable

Recruiting

• Conditions: Analgesia; Locoregional Anesthesia; Abdominoplasty; Quadratus Lumborum Block
• Interventions: Other: Intravenous anesthesia without QLB; Other: QLB anesthesia

• Registration Number: NCT04670224
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive ... Although they do not inevitably lead to a life-threatening prognosis, in many cases these complications delay post-operative recovery. Defined in the 1990s by Professor Henry Kehlet's Danish team, rapid rehabilitation after planned surgery is an approach to overall patient care that aims to rapidly restore previous physical and mental capacities and thus significantly reduce mortality and morbidity. Pain management is at the heart of this program and local anesthesia techniques are at the heart of early rehabilitation programs.

Described for just over a decade, Quadratus Lumborum Block (QLB) have shown their effectiveness for analgesia in abdominal, or orthopedic, or obstetrical surgery. Considering the anatomical territory concerned, this locoregional anesthesia technique seems to be very interesting in abdominoplasty to allow early rehabilitation of the patient.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-12-01
• Study First Submitted QC: 2020-12-10
• Study First Posted: 2020-12-17
• Study Start: 2021-03-16
• Status Verified: 2023-02
• Last Update Submitted: 2023-02-09
• Last Update Posted: 2023-02-10
• Primary Completion: 2023-12
• Study Completion: 2024-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 286

Inclusion Criteria

• Adult patients admitted for programmed dermo-lipectomy surgery with or without associated liposuction.

Exclusion Criteria

• Pregnant woman
• Patient under 18 years of age
• Subject under guardianship or curators
• Patient allergic to local anesthetics
• Infection at the puncture sites
• Patient on morphine analgesic over the long term
• Patient on antidepressants for neuropathic pain.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intravenous anesthesia without QLB	Intravenous anesthesia without QLB	-
QLB technique	QLB anesthesia	-

Primary Outcome Measures

Name	Time	Method
Variation from baseline of morphine consumption	24 hours after surgery

Secondary Outcome Measures

Name	Time	Method
Variation from baseline of morphine consumption	48 hours after surgery

Trial Locations

Locations (1)

BAR; 🇫🇷 Amiens, France