EPIDEMIOLOGY AND RISK FACTORS IN CHILDREN WITH AUTISM SPECTRUM DISORDER VISITING SIR SUNDERLAL HOSPITAL BHU
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- prenatal,
研究概览
简要总结
Autism Spectrum Disorder (ASD) is a biologically based neurodevelopmental disorder
characterized by core deficits in two key domains: social communication/interaction and
restrictive, repetitive patterns of behavior. The term "spectrum" in ASD acknowledges the
wide variability in how individuals are affected, with symptoms ranging from mild to severe,
often accompanied by overlapping comorbidities.
The prevalence of ASD is estimated at 1 in 59 persons by the U.S. Centers for Disease
Control and Prevention (CDC). The prevalence increased significantly over the past 25 years,
primarily because of improved diagnosis and case finding as well as inclusion of less severe
presentations within the autism spectrum. There is a 4:1 male predominance. The prevalence
is increased in siblings (up to 10% recurrence rate) and particularly in identical twins. There
are no racial or ethnic differences in prevalence. Individuals from racial minorities and lower
socioeconomic status are at risk for later diagnosis.
Autism: The Ayurvedic viewpoint
A behavioral abnormality with its roots situated in the malfunctioning neuropsychological system
and disorder in the digestive and metabolic system is considered to be an Unmada by Ayurveda.
There are places where one or more of the mental abilities can go wrong. There are various types
of inappropriate behavior shown by the person as a result of the distortion of the normal mind,
intellect, conscious awareness, memory, desire, manner, and behavior in the whole concept of
unmada.
In the concept of unmada, we see some of the affected faculties that can be seen in Autism
spectrum disorders. That involve impairments of
• Manas – mind-total or partial loss of sensory perception
• Buddhi—intellect—partially affected—could be irregular as shown in savant skill.
• Samjna Jnana – an aware presence – seen to be lost in their own environment, barring one
or more sensory stimuli.
• Bhakti – ability – inherent willingness to connect with others
• Seela – manners – socially inappropriate outbursts and adherence to strict rigid routines.
• Cheshta – Activities – Motor stereotypes that are improper and compulsive
• Achara – learned skills – poor socialization skills, failure to obey orders, loss of healthy
habits, etc.
• Knowledge of acquisition (Jnanotpathi), one of Manas; essential roles, is disrupted in
Unmada.
• Jnanotpathi occurs only when Manas is in tune with Atma (soul), Indriya (sense organ),
and Indriyartha (objects).
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 3.00 Year(s) 至 16.00 Year(s)(—)
- 性别
- All
入选标准
- •Children aged 3-16 years at the time of diagnosis, with a confirmed diagnosis of ASD based on DSM-5 criteria /ISAA Test.
排除标准
- •Children with incomplete medical records or those who do not meet the diagnostic criteria for ASD.
结局指标
主要结局
prenatal,
时间窗: prenatal, | perinatal and post natal influences, at registation and after 4 week | environmental exposures | medical history
perinatal and post natal influences,
时间窗: prenatal, | perinatal and post natal influences, at registation and after 4 week | environmental exposures | medical history
environmental exposures
时间窗: prenatal, | perinatal and post natal influences, at registation and after 4 week | environmental exposures | medical history
medical history
时间窗: prenatal, | perinatal and post natal influences, at registation and after 4 week | environmental exposures | medical history
次要结局
- To assess the age distribution of children diagnosed with ASD & identifies any significant(variations in risk factors among different age groups.)
研究者
Mohan Kumar
Institute of medical sciences, BHU
