Short duration of antibiotic therapy for treatment of catheter-related bloodstream infection caused by Gram-negative bacteria

Not Applicable

Completed

• Conditions: Catheter- related bloodstream infection caused by Gram- negative bacteria

• Registration Number: TCTR20190914001
• Lead Sponsor: Faculty of Pharmacy, Mahidol University, Thailand

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-07-14
• Study Start: 2019-09-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

1. Hospitalized patients with catheter-related bloodstream infection caused by culture proven Gram-negative bacteria
2. Patients receive appropriate antibiotic treatment

Exclusion Criteria

1. Patients without catheter removal
2. Patients have prosthetic valve or synthetic endovascular graft
3. Patients with neutropenia evaluated on antibiotic discontinuation day
4. Patients with persistent bacteremia, suppurative thrombophlebitis, septic emboli or other metastatic infectious complications such as infective endocarditis, septic arthritis, osteomyelitis, spondylodiscitis and deep-seated abscess evaluated on antibiotic discontinuation day
5. Patients have other indications for antibiotics that make them received antibiotic more than 7 days

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relapse at 7 days after antibiotic discontinuation Hemoculture

Secondary Outcome Measures

Name	Time	Method
Death within 30 days after antibiotic discontinuation Case review