Comparison of oxygenation and lung mechanics between two types of mechanical ventilatio
Not Applicable
- Conditions
- Respiratory failure that needs mechanical ventilation.Respiratory failure, unspecified
- Registration Number
- IRCT2013102215109N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
need to mechanical ventilation more than 1 week;
age between 20-50 years old;
normal pulmonary mechanic(C>50 and R<10)
Exclusion criteria:patient who death before 48 hours of admission in ICU;
History of asthma, COPD, bronchectasis, and other pulmonary disease;
history of liver, brain, heart and kidney disease;
inadequate spontaneous breathing;
refuse of patient
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Given Oxygen volume. Timepoint: every day for six days. Method of measurement: Manumeter.;Compliance. Timepoint: every day for six days. Method of measurement: Spirometer.;Pulmonery end expiratory pressure. Timepoint: every day for six days. Method of measurement: Ventilator.;100 mili second pressure. Timepoint: every day for six days. Method of measurement: pressure gauge.
- Secondary Outcome Measures
Name Time Method Pneumonia. Timepoint: every 3 days for six days. Method of measurement: Symptoms and lung CT scan.;Symptoms and imaging of acute respiratory distress syndrome. Timepoint: every 3 days for six days. Method of measurement: History taking and lung CT scan.;Symptoms of Ventilator related injury. Timepoint: every 3 days for six days. Method of measurement: History taking.;Cardiac output. Timepoint: every day for six days. Method of measurement: Echocardiography.;Asynchrony. Timepoint: every day for six days. Method of measurement: Symptoms.