Effect of Iron Deficiency Anemia on HBA1C in Patients With Diabetic Foot Ulcer Grade (1and2)

• Conditions: Iron Deficiency Anemia; HBA1C
• Interventions: Diagnostic Test: CBC ,Serum ferritin ,HBA1C

• Registration Number: NCT04131608
• Lead Sponsor: Assiut University

Brief Summary

Diabetic foot ulcer is the commonest cause of severe limb ischemia in diabetes mellitus And development of anemia is an additional burden to the microvascular complications of diabetes

Detailed Description

HBA1C is the predominant Hemoglobin found in HBA1 fraction and it constitutes 5% of total Hemoglobin in normal adults and up to 15%in patients with diabetes mellitus HBA1C is used to diagnose diabetes and to identify individuals that are at high risk for developing diabetes Iron deficiency anemia is one of the most prevalent form of malnutrition affect 1,62 billion people whish correspond to 24,8%of the world population Ferritin is the storage form of iron so it is found to be test for distinguishing those with iron deficiency anemia from those who are not iron deficient

Study Timeline

• Study First Submitted: 2019-09-25
• Study First Submitted QC: 2019-10-16
• Study First Posted: 2019-10-18
• Status Verified: 2020-10
• Last Update Submitted: 2021-01-11
• Last Update Posted: 2021-01-13
• Study Start: 2021-02-01
• Primary Completion: 2021-10-01
• Study Completion: 2021-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• all diabetic patients with diabetic foot ulcer grade one and two above 18 year

Exclusion Criteria

1. patients with anemia other than iron deficiency anemia
2. Patients on anticoagulants
3. patients with blood disease 4-patients below 18

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
diabetic foot ulcer (1and2)with iron defic	CBC ,Serum ferritin ,HBA1C	50 diabetic patients with diabetic foot ulcer grade (1and2) with iron deficiency anemia will be applied TO 1. cbc 2. ferritin 3. HBA1C 4. ankle brachial index by duplex
diabetic foot ulcer grade(1and2)without iron deficiency anemia	CBC ,Serum ferritin ,HBA1C	50 patients with diabetic foot ulcer grade (1and2) without iron deficiency anemia will be applied to 1. CBC 2. Ferritin, 3. HBA1C 4. ankle brachial index by duplex

Primary Outcome Measures

Name	Time	Method
Iron deficiency detected by Hemoglobin level in g/dl HBA1C level in diabetic patients	Base line	The influence of iron deficiency anemia on HBA1C in diabetic patients