NL-OMON46956已完成不适用
Cerebrovascular Reserve measUrements In Sickle cell diseasE, a MRI-based study - Cerebrovascular Reserve measUrements In Sickle cell diseasE/CRUISE
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- sickle cell disease (HbSS or HbS0)
- •- 18 years of age or older
- •- informed consent
排除标准
- •* inability of the patient to provide informed consent or legally incompetent/incapacitated to do so
- •* contraindications for MRI, such as pregnancy, claustrophobia or the presence of metal in the body
- •* sickle cell crisis at the moment of participation
- •* history of cerebral pathology that compromises measurements, such as cerebral palsy, brain tumor, meningitis, overt infarct
- •* brain surgery performed in the last 3 months
- •* severe liver, heart or renal dysfunction (clearance < 10 mL/min)
- •* allergy to sulfonamide
- •* breastfeeding
- •* use of phenytoin, procain, acetylsacylic acid (*Ascal/aspirine*)
- •* risk of hypokalemia (use of diuretics, primary hyperaldosteronism)
- •* Addison*s Disease
- •* severe asthma or emphysema
研究者
相似试验
Unknown
不适用
Cerebrovascular Reserve Measurements in Sickle Cell DiseaseSickle Cell DiseaseNCT02824406Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)60
尚未招募
不适用
Cerebral Perfusion Imaging in Children with Sickle Cell DiseaseHereditary anemia100381581002766410007963Sickle cell diseaseNL-OMON33195Academisch Medisch Centrum50
已完成
不适用
Cerebrovascular Involvement in Sickle Cell Disease - Comprehensive Sickle Cell CenterAnemia, Sickle CellCerebrovascular AccidentBlood DiseaseNCT00005326National Heart, Lung, and Blood Institute (NHLBI)
已完成
不适用
Measurement of cerebrovascular reserve using 3D-ASL MRIObstructive cerebrovascular diseaseJPRN-UMIN000011162Kitasato University, School of Medicine8
已完成
不适用
Prevention of Cerebral Infarction in Sickle Cell Anemia - Comprehensive Sickle Cell CenterAnemia, Sickle CellCerebrovascular DisordersCerebrovascular AccidentBlood DiseaseNCT00005327University of Southern California