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A single-center, prospective, randomized trial to evaluate the efficacy of ablation using the spatiotemporally distributed potentials visualized by a fractionation map compared with ablation using low-potential regions visualized by a voltage map in patients with recurrent sustained atrial fibrillation (ARCHERY trial).

Phase 2
Recruiting
Conditions
Recurrent Persistent Atrial Fibrillation
Registration Number
JPRN-jRCTs042230101
Lead Sponsor
aruse Yoshihisa
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

1. patients over 18 years of age
2. Patients undergoing a second catheter ablation for recurrent persistent AF after initial pulmonary vein isolation
3. Patients who have given their consent to participate in this study by signing a consent form in person.

Exclusion Criteria

1. patients with AF arrest at the time of EPS
2. patients with no STDE at the time of EPS
3. patients with pulmonary veins (PV) re-conduction at the time of EPS
4. patients with allergy or serious renal disorder that precludes pre- and post-operative contrast-enhanced cardiac CT
5. patients with severely enlarged left atrium (left atrial volume >200 ml on preoperative CT analysis)
6. patients with severe left ventricular systolic dysfunction (LVEF <40%)
7. patients with symptomatic heart failure (NYHA grade III or higher)
8. other patients deemed unsuitable by the principal investigator (subinvestigator)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
AF burden: Percentage of AF duration 52 weeks after catheter ablation
Secondary Outcome Measures
NameTimeMethod
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