An Analysis of Urinary Proteases as Biomarkers for Hepatocellular Carcinoma-101423

Completed

• Conditions: Hepatocellular Carcinoma; Liver Disease

• Registration Number: NCT01316679
• Lead Sponsor: Vanderbilt University Medical Center

Brief Summary

Specific urine proteases or groups of these enzymes can be reliable biomarkers and an effective gauge of response to therapy in patients with hepatocellular carcinoma.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-03
• Study First Submitted: 2011-03-15
• Study First Submitted QC: 2011-03-15
• Study First Posted: 2011-03-16
• Primary Completion: 2013-01
• Study Completion: 2013-01
• Status Verified: 2017-04
• Last Update Submitted: 2017-04-10
• Last Update Posted: 2017-04-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 87

Inclusion Criteria

• Ability and willingness to provide written informed consent
• Must be between 18-90 years of age at the time of consent
• Ability to provide urine specimen at protocol-defined timepoints
• Must have treatment interventions planned that are directly related to liver disease (excluding those assigned to group 3-Controls)

Exclusion Criteria

• Suspected inability, e.g. unwillingness to comply with study procedures or unwillingness to provide written consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified