Efficacy of Nepeta Menthoides in depressio

Phase 3

Conditions: Condition 1: Depression. Condition 2: Anxiety.
Mild depressive episode, moderate depressive episode, recurrent depressive disorder current episode mild, recurrent depressive disorder current episode moderate
Other anxiety disorders
F32.0, F32

Registration Number: IRCT2015031521469N1

Lead Sponsor: Vice chancellor for research, Shiraz University of Medical Science

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 60

Inclusion Criteria

Adult outpatients between 18-65 referring to psychiatry clinic of Shiraz medical university; meet Becks depression inventory (BDI-II) and DSM-V-TR criteria for mild to moderate major depression; confirmation of the diagnosis by at least two psychiatrist; and informed consent.
Exclusion criteria: Having other conditions assuming depression such as: hypothyroidism, psychiatric disorders except for mild to moderate major depression, mental disorders i.e. dementia
or mental retardation; allergy to Nepeta Menthoides or other mentheae family (Lamiaceaes); substance dependency; pregnancy; suicidal thinking or needing to electroconvulsive therapy; not having informed consent

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of depression. Timepoint: At the base line,2nd week, 4th week after beginning of intervention and then in 6th week (2 weeks after the end of intervention). Method of measurement: Beck depression inventory(BDI-II) score.

Secondary Outcome Measures

Name	Time	Method
Side effects profile. Timepoint: At the base line, 2nd week, 4th week after beginning of intervention and then in 6th week (2 weeks after the end of intervention). Method of measurement: Clinical interview and physical examination and list in a table.;Severity of anxiety. Timepoint: At the base line, 2nd week, 4th week after beginning of intervention and then in6th week (2 weeks after the end of intervention). Method of measurement: Beck anxiety inventory (BAI) score.