The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer

Not Applicable

Recruiting

• Conditions: Colon Cancer

• Registration Number: NCT05859581
• Lead Sponsor: Peking University Cancer Hospital & Institute

Brief Summary

The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer.

The main questions it aims to answer are:

* Concordance between MRI suspected RPRM positive and pathologically confirmed positive.

* Can RPRM-positive patients undergo beyond complete mesocolic excision (CME) surgery in order to achieve R0 resection?

Participants will undergo colon MRI examination and once MRI suspects RPRM positive, they will receive beyond CME surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-04-02
• Status Verified: 2023-05
• Study First Submitted: 2023-05-05
• Study First Submitted QC: 2023-05-05
• Last Update Submitted: 2023-05-05
• Study First Posted: 2023-05-16
• Last Update Posted: 2023-05-16
• Primary Completion: 2023-08-31
• Study Completion: 2023-08-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 29

Inclusion Criteria

• primary colon adenocarcinoma confirmed by biopsy
• preoperative CT suspecting retroperitoneal resection margin (RPRM) positive
• received colon MRI scan
• underwent beyond complete mesocolic excision surgery
• sufficient clinical and pathological results

Exclusion Criteria

• combined with other malignant tumors
• simultaneous distant metastasis
• definite invaded other organs or structures (T4b tumors)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Coincidence rate with pathological result	within 2 weeks after surgery	Coincidence rate between MRI diagnosed retroperitoneal resection margin and pathologically confirmed positive

Trial Locations

Locations (1)

Beijing Cancer Hospital; 🇨🇳 Beijing, Beijing, China