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Clinical Trials/NCT05859581
NCT05859581
Recruiting
Not Applicable

To Explore the Value of Colon MRI in Assessing the Status of Retroperitoneal Resection Margin Following Beyond Complete Mesocolic Excision Surgery for Advanced Colon Cancer

Peking University Cancer Hospital & Institute1 site in 1 country29 target enrollmentApril 2, 2023
ConditionsColon Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colon Cancer
Sponsor
Peking University Cancer Hospital & Institute
Enrollment
29
Locations
1
Primary Endpoint
Coincidence rate with pathological result
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer.

The main questions it aims to answer are:

  • Concordance between MRI suspected RPRM positive and pathologically confirmed positive.
  • Can RPRM-positive patients undergo beyond complete mesocolic excision (CME) surgery in order to achieve R0 resection?

Participants will undergo colon MRI examination and once MRI suspects RPRM positive, they will receive beyond CME surgery.

Registry
clinicaltrials.gov
Start Date
April 2, 2023
End Date
August 31, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
Peking University Cancer Hospital & Institute
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • primary colon adenocarcinoma confirmed by biopsy
  • preoperative CT suspecting retroperitoneal resection margin (RPRM) positive
  • received colon MRI scan
  • underwent beyond complete mesocolic excision surgery
  • sufficient clinical and pathological results

Exclusion Criteria

  • combined with other malignant tumors
  • simultaneous distant metastasis
  • definite invaded other organs or structures (T4b tumors)

Outcomes

Primary Outcomes

Coincidence rate with pathological result

Time Frame: within 2 weeks after surgery

Coincidence rate between MRI diagnosed retroperitoneal resection margin and pathologically confirmed positive

Study Sites (1)

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