The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer
Not Applicable
Recruiting
- Conditions
- Colon Cancer
- Interventions
- Procedure: Beyond complete mesocolic excision surgery
- Registration Number
- NCT05859581
- Lead Sponsor
- Peking University Cancer Hospital & Institute
- Brief Summary
The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer.
The main questions it aims to answer are:
* Concordance between MRI suspected RPRM positive and pathologically confirmed positive.
* Can RPRM-positive patients undergo beyond complete mesocolic excision (CME) surgery in order to achieve R0 resection?
Participants will undergo colon MRI examination and once MRI suspects RPRM positive, they will receive beyond CME surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 29
Inclusion Criteria
- primary colon adenocarcinoma confirmed by biopsy
- preoperative CT suspecting retroperitoneal resection margin (RPRM) positive
- received colon MRI scan
- underwent beyond complete mesocolic excision surgery
- sufficient clinical and pathological results
Exclusion Criteria
- combined with other malignant tumors
- simultaneous distant metastasis
- definite invaded other organs or structures (T4b tumors)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Suspected positive RPRM on MRI Beyond complete mesocolic excision surgery -
- Primary Outcome Measures
Name Time Method Coincidence rate with pathological result within 2 weeks after surgery Coincidence rate between MRI diagnosed retroperitoneal resection margin and pathologically confirmed positive
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Beijing Cancer Hospital
🇨🇳Beijing, Beijing, China