NCT05859581RecruitingNot Applicable
To Explore the Value of Colon MRI in Assessing the Status of Retroperitoneal Resection Margin Following Beyond Complete Mesocolic Excision Surgery for Advanced Colon Cancer
Peking University Cancer Hospital & Institute1 site in 1 country29 target enrollmentStarted: April 2, 2023Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 29
- Locations
- 1
- Primary Endpoint
- Coincidence rate with pathological result
Study Overview
Brief Summary
The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer.
The main questions it aims to answer are:
- Concordance between MRI suspected RPRM positive and pathologically confirmed positive.
- Can RPRM-positive patients undergo beyond complete mesocolic excision (CME) surgery in order to achieve R0 resection?
Participants will undergo colon MRI examination and once MRI suspects RPRM positive, they will receive beyond CME surgery.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •primary colon adenocarcinoma confirmed by biopsy
- •preoperative CT suspecting retroperitoneal resection margin (RPRM) positive
- •received colon MRI scan
- •underwent beyond complete mesocolic excision surgery
- •sufficient clinical and pathological results
Exclusion Criteria
- •combined with other malignant tumors
- •simultaneous distant metastasis
- •definite invaded other organs or structures (T4b tumors)
Outcomes
Primary Outcomes
Coincidence rate with pathological result
Time Frame: within 2 weeks after surgery
Coincidence rate between MRI diagnosed retroperitoneal resection margin and pathologically confirmed positive
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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