Pulmonary Determinants of Cardiorespiratory Fitness in Patients With Fontan Procedure
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Fontan Procedure
- Sponsor
- Hacettepe University
- Enrollment
- 78
- Locations
- 1
- Primary Endpoint
- FEV1/FVC
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
This study will examine and record the patient's medical information and medical records (patient files, computer records, etc.). Physical examination, echocardiographic, electrocardiographic, laboratory, radiological, etc. evaluations are made during the routine controls of the patients. Within the scope of this study, no attempt will be made on the patients, no additional tests will be performed, or treatment changes will not be made in the patients because they are included in this study. After these records, KPET will be performed by a specialist doctor and physiotherapist for the patients who are directed to the Faculty of Physical Therapy and Rehabilitation Cardiopulmonary Rehabilitation Unit. Pulmonary function tests and respiratory muscle strength measurements will be performed on patients who have adequate rest after CPET.
Investigators
Haluk TEKERLEK
Research assistant
Hacettepe University
Eligibility Criteria
Inclusion Criteria
- •Be between 8-55 years old
- •Having undergone a Fontan operation
- •Clinical stability of the patients (preserved ventricular function)
- •No change in ongoing drug therapy that adversely affects clinical stability
- •At least 1 year after the operation
- •Fontan Group
Exclusion Criteria
- •Neurological and/or genetic musculoskeletal disease
- •Having orthopedic and cognitive problems that prevent testing
- •The patient's and/or family's unwillingness to participate in the study
- •Control Group Inclusion Criteria:
- •Not have cardiovascular, neurological, and/or genetic musculoskeletal disease
- •Not having orthopedic and cognitive problems that prevent testing
- •The patient's and/or family's willingness to participate in the study
Outcomes
Primary Outcomes
FEV1/FVC
Time Frame: 15-20 minutes
Maximal inspiratory pressure
Time Frame: 15-20 minutes
Ratio curve of minute ventilation to carbon dioxide production (VE/VCO2) slope
Time Frame: 30-45 minutes
Ratio of minute ventilation to carbon dioxide production (VE/VCO2)
Time Frame: 30-45 minutes
Oxygen uptake efficiency slope (OUES)
Time Frame: 30-45 minutes
Maximal oxygen consumption
Time Frame: 30-45 minutes
Forced vital capacity (FVC)
Time Frame: 15-20 minutes
Forced expiratory volume in 1 second (FEV1)
Time Frame: 15-20 minutes
Maximal expiratory pressure
Time Frame: 15-20 minutes
Minute ventilation (VE)
Time Frame: 30-45 minutes
End tidal carbon dioxide pressure (PetCO2)
Time Frame: 30-45 minutes
End tidal oxygen pressure (PetO2)
Time Frame: 30-45 minutes