Comparison of postoperative analgesic effect of intravenous acetaminophen versus intravenous caffeine in distal radius surgery

Phase 3

Recruiting

• Conditions: distal radius surgery.; Fracture of lower end of radius; S52.5

• Registration Number: IRCT20230716058807N1
• Lead Sponsor: Qazvin University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 August 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Willingness to participate in research with informed consent after giving necessary and sufficient explanations about the study
Age 20 to 60 years
Distal radius fracture
General anesthesia

Exclusion Criteria

Unwillingness to cooperate in the study
Cardiac patients with a history of HTN (heart rate over 100 during surgery/blood pressure over 140 mm Hg during surgery)
Occurrence of any problems and complications during the study
Pregnancy, breastfeeding and abortion less than 3 months
Allergy to acetaminophen/caffeine/morphine
Long-term use of corticosteroids, antihistamines, narcotics and pain relievers
Vision and hearing problems and other disabilities
Chronic mental and physical illness (schizophrenia, diabetes, etc)
Liver patients (hepatitis, cirrhosis, etc.)
History of smoking, alcohol and drugs
The duration of surgery should be less than 45 minutes

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The amount and intensity of pain. Timepoint: 1, 3, 6 and 12 hours after the operation. Method of measurement: Using a ruler-like grading system (Visual Analog Scale) from 0 (no pain) to 10 (the most severe pain imaginable).