Interpersonal Psychotherapy for Depression With Co-occurring Panic and Anxiety Symptoms (IPT-PS)
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Depression
- Sponsor
- University of Pittsburgh
- Enrollment
- 36
- Locations
- 1
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
This 6-month study, with a 3-month follow up period, will compare the effectiveness of new and traditional psychotherapies for depression with panic or anxiety symptoms.
Detailed Description
Many depressed patients also experience significant symptoms of panic or anxiety. This study will compare the effectiveness of a new therapy called interpersonal psychotherapy for depression with panic or anxiety symptoms (IPT-PS) with that of traditional interpersonal psychotherapy for depression (IPT). Participants are randomly assigned to receive up to 24 weeks of treatment with either IPT-PS or traditional IPT. Improvements in interpersonal functioning, quality of life, and symptoms of depression and anxiety will be assessed at the end of therapy and at a 3-month follow-up.
Investigators
Eligibility Criteria
Inclusion Criteria
- •DSM-IV diagnosis of major depression with co-existing panic or anxiety symptoms.
Exclusion Criteria
- •History of manic episode(s). Patients who have had hypomanic episodes in the past will be accepted into the study, provided they meet other admission criteria and are not presenting in a current hypomanic or mixed episode.
- •History of schizophrenia or schizoaffective disorder.
- •Organic affective syndrome.
- •Unspecified functional psychosis.
- •Anorexia nervosa or bulimia nervosa. Patients meeting criteria for an eating disorder not otherwise specified will not be excluded.
- •Chronic drug or alcohol abuse/dependence within the past 2 years. Patients with abuse related to episodes will not be excluded.
- •DSM-IV criteria for borderline or antisocial personality disorder. Patients who meet criteria for other Axis II disorders will not be excluded.
- •Inpatient treatment due to suicide risk or psychotic symptoms.
- •Index episode secondary to the effect of medically prescribed drugs.
- •Significant or untreated medical illness, including cardiovascular disorder, renal or liver disease, epilepsy, untreated hypertension, or unstabilized endocrine disease.
Outcomes
Primary Outcomes
Not specified