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Clinical Trials/NCT04498195
NCT04498195
Completed
N/A

Effect of a Walking Intervention on Cognitive Function in Individuals With Mild Cognitive Impairment: A Knowledge Translation to Practice Pilot Project

Samuel Merritt University1 site in 1 country17 target enrollmentJanuary 7, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cognitive Impairment, Mild
Sponsor
Samuel Merritt University
Enrollment
17
Locations
1
Primary Endpoint
Whether increasing the number of daily steps among older adults with mild cognitive impairment would improve their cognitive functioning.
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Background: Many studies suggest physical activity reduces risk of dementia and improves global cognitive function in individuals with mild cognitive impairment (MCI). Using commercial wearable technology to measure daily steps is feasible in this population.

Objectives: The purpose of this pilot study was to explore whether 12 weeks of increased physical activity improved cognitive function in individuals with MCI. A wearable activity tracker was used to measure participants' daily steps as a quantifiable measure of daily activity level.

Design: This was a one-group pretest-posttest study.

Setting: Established memory clinic patients within a neurology department in Northern California during 2019.

Participants: 17 enrolled and 14 included for data analysis. There were 7 females and 7 males whose mean age was 76.21 (SD 2.69). 12 participants were White, which reflected the clinic population.

Intervention: Participants were asked to wear an activity tracker for approximately 12 hours a day for 12 weeks and to increase their physical activity as much as possible. They were provided twice a month telephone support.

Measurements: The Montreal Cognitive Assessment (MoCA) was used to measure pretest-posttest cognitive function. Timed Up and Go (TUG) was used to assess fall risk at enrollment. Cumulative step count for the study period was measured with an activity tracker.

Registry
clinicaltrials.gov
Start Date
January 7, 2019
End Date
December 6, 2019
Last Updated
5 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Gasong Yun Nickerson

DNP graduate

Samuel Merritt University

Eligibility Criteria

Inclusion Criteria

  • Participants had a score of 0.5 on the Clinical Dementia Rating and are on a stable medication regimen for 3 months prior to enrollment.

Exclusion Criteria

  • a diagnosis of dementia; receiving chemotherapy; unstable chronic diseases; surgery with general anesthesia in the prior 3 months; MRI-confirmed brain damage from trauma, stroke, or other neurological disorder; a myocardial infarction \< 1 year; a serious or non-healing wound, ulcer, or bone fracture; TUG ≥ 12 seconds; MoCA score \>26 or \<16; already using a wearable activity tracker; lacked access to the internet; or non-English speaking.

Outcomes

Primary Outcomes

Whether increasing the number of daily steps among older adults with mild cognitive impairment would improve their cognitive functioning.

Time Frame: 12 weeks

participants would wear an activity tracker and increase physical activity as much as possible within their comfort level. Participants will be tested for pretest MoCA for cognitive function and TUG for fall risk. After 12 weeks, participants will be tested for posttest MoCA to find any cognitive function change.

Study Sites (1)

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