NCT00588029进行中（未招募）不适用
Collection of Tissue, Blood, and Cells to Be Used For Studying the Causes, Prevention, Diagnosis, and Treatment of Breast Cancer
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 7,000
- 试验地点
- 3
- 主要终点
- None. This is a tissue banking study.
研究概览
简要总结
The purpose of this study is to collect a blood sample from patients with breast disease (cases) and from individuals without breast cancer (controls)that may be used for research purposes. These blood samples will be used by researchers at Memorial Sloan-Kettering Cancer Center who study the causes of breast cancer, as well as more effective ways to prevent, diagnose, and treat breast cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For acquisition of existing breast cancer tissue specimens from the MSKCC Tissue Procurement Service, the only criteria are a pathologically-confirmed diagnosis of invasive breast cancer and the availability of corresponding nonmalignant tissue from each case.
- •For the prospective acquisition of blood or saliva from control subjects without breast cancer, eligibility criteria include:
- •Any patient with a previous diagnosis of invasive breast cancer who undergoes a palliative procedure related to the presence of a pleural effusion is eligible for the pleural fluid collection aspect of this protocol.
- •Any female patient, or any female over the age of 18 accompanying a patient under the care of a physician in the Department of Urology, Department of Surgery, or Department of Medicine.
- •Subjects will have no history of preinvasive (carcinoma in situ) or invasive breast cancer.
- •Subjects will be eligible without regard to racial, or ethnic status. Attending physicians authorized to obtain informed consent may exercise discretion in excluding individuals for appropriate medical or other (e.g., mentally impaired) reasons.
- •For the prospective acquisition of blood, saliva, pleural fluid or cerebrospinal fluid from patients who have or are suspected of having breast cancer or carcinoma in-situ, eligibility criteria include:
- •Any patient at MSKCC with a previously confirmed or suspected diagnosis of malignant or premalignant (e.g., carcinoma in situ) breast disease is eligible for inclusion in the blood acquisition aspect of this protocol.
- •Any patient with a previous diagnosis of invasive breast cancer who undergoes a palliative procedure related to the presence of a pleural effusion is eligible for the pleural fluid collection aspect of this protocol.
- •Any patient with a previous diagnosis of invasive breast cancer with leptomeningeal metastasis who undergoes a routine procedure associated with the collection of cerebrospinal fluid is eligible for the cerebrospinal fluid collection aspect of this protocol.
- •All subjects must be under the care of one or more members of the MSKCC Breast Disease Management Team at the time of enrollment.
- •Subjects may have received prior hormonal therapy, cytotoxic chemotherapy, radiation therapy, or surgical therapy at MSKCC or another institution.
- •All subjects must be 18 years or older
- •Subjects will be eligible without regard to sex, racial, or ethnic status. It is anticipated that approximately 99% of the patients will be female. Attending physicians authorized to obtain informed consent may exercise discretion in excluding individuals for appropriate medical or other (e.g., mentally impaired) reasons.
- •If, after pathologic diagnosis, preinvasive or invasive breast disease is not found, patients previously consented for the blood collection aspect of this protocol will not be included.
排除标准
- •For the prospective acquisition of blood or saliva from control subjects without breast cancer, ineligibility criteria include:
- •A first degree relative (mother, daughter, sister, father, brother or son) who has been diagnosed with breast cancer.
- •A personal history of breast cancer, lobular carcinoma in situ or atypia.
研究组 & 干预措施
1
breast cancer patients
2
control subjects without breast cancer
结局指标
主要结局
None. This is a tissue banking study.
时间窗: 1 year
次要结局
未报告次要终点
研究者
研究点 (3)
Loading locations...
相似试验
终止
不适用
Sample Collection From Melanoma PatientsMelanomaNCT00507325M.D. Anderson Cancer Center131
已完成
不适用
Tissue Samples and Bodily Fluid Specimens BankingEndocrine Disorders of Female Reproductive SystemNCT02431884University of Tennessee200
已完成
不适用
Collection of Blood, Bone Marrow, Tumor or Tissue SamplesNeoplasmsPrecancerous ConditionsNCT00043615National Cancer Institute (NCI)74
招募中
不适用
Collecting and Storing Tissue Samples From Women With or Without Breast CancerBreast CancerNCT00899301Vanderbilt-Ingram Cancer Center4,000
进行中（未招募）
不适用
Questionnaire and Tissue Banking For Multiple Myeloma, Waldenstrom Macroglobulinemia and Related DisordersWaldenstrom's MacroglobulinemiaSmoldering Multiple MyelomaLymphoblastic LymphomaMultiple MyelomaNCT01177527Dana-Farber Cancer Institute656