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Transvaginal Pelvic Ultrasound in the ED

Completed
Conditions
Pelvic Pain
Abdominal Pain
Interventions
Other: Pelvic US
Registration Number
NCT02547857
Lead Sponsor
Hennepin Healthcare Research Institute
Brief Summary

Pelvic ultrasound is frequently performed in the ED in non-pregnant women to assess for ovarian pathology, though its use has not been described in the medical literature. This observational study aims to describe its use in clinical ED practice.

Detailed Description

Pelvic ultrasound is frequently performed in the ED in non-pregnant women to assess for ovarian pathology. During the pelvic examination a transvaginal ultrasound probe is used to visualize ovarian size, determine echotexture, assess whether ovarian tenderness is present, and sometimes measure ovarian blood flow. Though pelvic ultrasound is used in the Hennepin County Medical Center ED routinely, there is a paucity of literature assessing it's utility.

This observational study will help determine the usefulness of this imaging modality, and how often it changes management in clinical practice.

Specifically, this study will attempt to determine how often transvaginal ultrasound identifies the structures of interest, and then will correlate these findings with the final ED diagnosis. If a formal ultrasound is obtained, the findings of the ED ultrasound will also be compared to the findings of the formal ultrasound.

The treating physicians will be queried the diagnosis and management plans before and after the pelvic US to ascertain changes in management.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
114
Inclusion Criteria
  • Age >= 18 years old female
  • ED bedside transvaginal ultrasound to be performed in a non-pregnant woman with at least one ovary
  • Willing to discuss how they are doing at 7-10 days via phone
  • Valid phone number
Exclusion Criteria
  • If a diagnosis of ovarian torsion, mass, TOA or other ovarian pathology is known before ED ultrasound
  • Previously enrolled in this study

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Cohort 1Pelvic USAll women who undergo pelvic US in the ED, assuming they meet inclusion/exclusion criteria
Primary Outcome Measures
NameTimeMethod
Change in diagnosis before/after pelvic US8 hours (or less, this will measure what occurs during an ED stay)

The treating physician will be queried the likelihood of EMERGENT and NON-EMERGENT ovarian pathology before and after pelvic US using the following scale: Definite, Probable, Possible, Very Unlikely. The ED tests reviewed before each of these judgements will be noted. EMERGENT is defined as ovarian torsion or tubo-ovarian abscess (TOA). NON-EMERGENT is defined as all other causes, including ovarian cyst, ovarian mass, ovarian malignancy, adnexal mass). The clinician will also free text the most likely diagnosis. A change of two or more levels (eg definite to possible, definite to very unlikely, probable to very unlikely, or vice versa) will be assumed to be a significant change in diagnosis.

Change in management plan before/after pelvic US8 hours (or less, this will measure what occurs during an ED stay)

The treating physician will choose from the following regarding the management plan before/after the pelvic US: outpatient referral to OB/GYN, formal pelvic US after bedside US, consult GYN in the ED, urgent/emergent operative intervention, None of the above. Any difference in management before/after pelvic US will be considered a significant change in management.

Secondary Outcome Measures
NameTimeMethod
Duration of pelvic US8 hours (or less, this will measure what occurs during an ED stay)

Less than 5 minutes, 5-10 minutes, more than 10 minutes

Sonographic visualization of ovaries8 hours (or less, this will measure what occurs during an ED stay)

yes/no

Ovary enlargement8 hours (or less, this will measure what occurs during an ED stay)

Were the ovaries larger than 3.5 x 2 cm in any plane? yes/no answer

Ovarian tenderness, sonographic8 hours (or less, this will measure what occurs during an ED stay)

As a dichotomous yes/no. This will be correlated to final diagnosis. How many women with a non-tender ovary ended up with EMERGENT pathology? How many had NON-EMERGENT pathology?

Ovarian blood flow8 hours (or less, this will measure what occurs during an ED stay)

The physician will determine if the ovarian flow is normal in a dichotomous yes/no answer. (if performed)

ED disposition after visit8 hours (or less, this will measure what occurs during an ED stay)

This will measure if the patient is discharged from the ED or admitted to the hospital

Final ED diagnosis8 hours (or less, this will measure what occurs during an ED stay)

Two questions will be answered:

1. Ovarian Pathology, Emergency (tubo-ovarian abscess, torsion)

2. Ovarian Pathology, Non-Emergency (cyst, mass, malignancy)

3. Non-ovarian problem

Question 2:

Final ED diagnosis after all work-up: (select all that apply) checkbox

1. ed_final_dx_2___1 ovarian cyst

2. ed_final_dx_2___2 ovarian mass

3. ed_final_dx_2___3 ovarian torsion

4. ed_final_dx_2___4 tubo-ovarian abscess

5. ed_final_dx_2___5 other ovarian pathology

6. ed_final_dx_2___6 adnexal mass (non-ovarian)

7. ed_final_dx_2___7 Pelvic Inflammatory Disease

8. ed_final_dx_2___8 Abdominal pathology (appendicitis, diverticulitis, SBO, others)

9. ed_final_dx_2___9 Non-specific abdominal pain

10. ed_final_dx_2___10 None of the above and no ovarian pathology suspected

7-day follow-up7 days

Whether another facility was visited, whether a procedure occurred, and what else happened during this stay. Patients will be attempted to be contacted three times.

Correlation between ED US and Formal US8 hours (or less, this will measure what occurs during an ED stay)

If a formal US is obtained, the reading will be abstracted and compared to the ED US for the following: ovary visualization, ovary size, ovarian flow, final diagnosis, and any other abnormality in free text.

Final impression for ED ultrasound with regards to ovaries8 hours (or less, this will measure what occurs during an ED stay)

NORMAL or ABNORMAL. If abnormal, the abnormality will be described.

Formal pelvic US8 hours (or less, this will measure what occurs during an ED stay)

Was this study obtained? dichotomous yes/no. And why was a formal pelvic US obtained? (abnormality of ovaries on bedside US; other abnormality on bedside US; unable to visualize ovaries on bedside US; good visualization of all structures and all structures normal, but post-test probability still high; Other (free text). )The exact reason will then be listed in free text.

Trial Locations

Locations (1)

Hennepin County Medical Center

🇺🇸

Minneapolis, Minnesota, United States

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