Intracoronary Injection of Autologous Bone Marrow Cells in Patients With Chronic Heart Failure: Five Years Follow up

Assaf-Harofeh Medical Center1 site in 1 country8 target enrollmentApril 2003

ConditionsChronic Ischemic Symptomatic Heart Failure

Overview

Phase: Phase 2
Intervention: Not specified
Conditions: Chronic Ischemic Symptomatic Heart Failure
Sponsor: Assaf-Harofeh Medical Center
Enrollment: 8
Locations: 1
Primary Endpoint: Procedure success
Status: Completed
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The study aim is to evaluate the long term outcome of intra-coronary autologous bone marrow (BM) transplantation in patients with severe ischemic cardiomyopathy without the option for revascularization.

Detailed Description

Several studies have demonstrated the short term safety, feasibility and efficacy of cell transplantation in patients with advanced heart failure. There are no data about the long term outcome.

Registry

clinicaltrials.gov

Start Date

April 2003

End Date

December 2003

Last Updated

16 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Assaf-Harofeh Medical Center

Eligibility Criteria

Inclusion Criteria

•Patients with evidence of hibernation and/or ischemia in at least 2 different myocardial segments underwent coronary angiography

Exclusion Criteria

•Idiopathic or non-ischemic cardiomyopathy
•Other etiology for heart failure, history of past or current disease involving the bone marrow
•Patients on dialysis
•Positive serologic test for HIV, hepatitis B or C or any neoplastic or terminal disease