Effect of the combination of artificial dura and umbilical cord and placenta mesenchymal stem cell-derived exosomes in patients with complete spinal cord injury

Not Applicable

• Conditions: Complete spinal cord injury.; Injury of spinal cord, level unspecified; T09.3

• Registration Number: IRCT20200502047277N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 3 April 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Traumatic spinal cord injury
Time from injury up to 36 months
Complete spinal cord injury (class A in ASIA scale)
Written informed consent

Exclusion Criteria

History of previous spinal surgery
Amputation
Having underlying diseases affecting the diagnosis and treatment process (such as: diabetes mellitus, osteopenia, spinal cord injury, etc.)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Motor score of the American Spinal Injury Association Impairment Scale. Timepoint: Before treatment, 3, 6, and 12 months after injury. Method of measurement: Physical examination.;Sensory score of the American Spinal Injury Association Impairment Scale. Timepoint: Before treatment, 3, 6, and 12 months after injury. Method of measurement: Physical examination.;Mean of the Spinal Cord Independence Measure III scores of patients. Timepoint: Before treatment, 3, 6, and 12 months after injury. Method of measurement: Spinal Cord Independence Measure III questionnaire.