Vitamin K and arterial calcificatio
- Conditions
- Vitamin K, menaquinone-7, arterial calcification, dp-ucMGP, diabetes patiënts, arterial stiffness, bone metabolism.
- Registration Number
- NL-OMON25255
- Lead Sponsor
- MC Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Middle aged men and women ¡Ý 40 years.
- Diagnosed with type 2 diabetes.
Exclusion Criteria
- Contra-indication for undergoing 18F-NaF PET/CT scan (pregnancy, breastfeeding, recent radiotherapy or chemotherapy).
- Subject underwent amputation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Arterial calcifications as quantified by 18F-NaF PET/CT imaging.
- Secondary Outcome Measures
Name Time Method - Arterial calcification in other arteries than the femoral artery as quantified by 18F-NaF PET/CT imaging.<br /><br>- Bone metabolism in the lumbar spine, as quantified by 18F-NaF PET/CT imaging.<br /><br>- Arterial stiffness, as quantified by pulse wave velocity measurement.<br /><br>- Dpuc-MGP, as quantified using a sandwich ELISA.