Evaluation of curative effect of traditional Chinese medicine for nourishing yin, clearing heat, resolving phlegm and resolving stagnation on Graves' disease based on Markov model

适应症

试验速览

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•1. Conform to the diagnosis of Graves disease; 2. TCM syndrome differentiation is yin deficiency and phlegm-heat syndrome; 3. Age between 18 and 65 years old, gender is not limited; 4. During the lead-in period of the test, FT3 and FT4 were higher than the normal value range, and TSH was lower than the normal value range; 5. The patients voluntarily signed the informed consent.

•1.Hyperthyroidism caused by other reasons or not in line with TCM syndrome differentiation of yin deficiency and phlegm heat; 2. Patients with hyperthyroidism crisis and co-infection within the past 1 month; 3. Those who are unwilling to cooperate (referring to those who cannot cooperate with dietary control or do not take medication as prescribed, and who cannot regularly monitor thyroid function as prescribed by a doctor) and mentally ill patients; 4. Pregnant or lactating women, those who plan to become pregnant; 5. Combined with obvious cardiovascular disease (New York Heart Association grade 2 or 3), abnormal liver function (ALTT and AST higher than 1 times the upper limit of normal), abnormal renal function (creatinine greater than 200µmol/L), brain Primary diseases such as vascular disease (acute phase) and hematopoietic system disease (requiring treatment); 6. Allergic constitution or allergic history to multiple drugs (two or more or known ingredients in the drug); 7. Patients with thyroid cancer and other malignant tumors; 8. Patients with active thyroid eye disease; 9. Those who have participated in clinical trials of other drugs within the past 4 weeks; 10. Those who are considered inappropriate by the investigator to participate in clinical trials.

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