IRCT20140818018842N27已完成3 期
A study to evaluate the efficacy of Atorvastatin in the prophylaxis of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation (HSCT)
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 75
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 60 years（—）
- 性别
- All
入选标准
- •Donor age : 18 years or above
- •Normal liver function in donors
- •Normal renal function in recipients
- •KPS =>60 for donors
- •Patients with a history of hematologic malignancies or bone marrow failure syndromes
- •Recipient age: 18 to 60 years
- •A fully HLA-matched family donor
- •LVEF=>40% for recipients
- •Normal liver function in recipients
- •Normal renal function in donors
- •KPS =>70 for recipients
- •There is no no prohibition for patients who already received Atorvastatin
排除标准
- •Pregnant women and lactating mothers
- •Positive history of hypersensitivity to Atorvastatin in donors
- •HIV-positive donors
- •HIV-positive recipients
- •Positive history of hypersensitivity to Atorvastatin in recipients
- •Patients receiving ATG
研究者
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