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临床试验/CTRI/2024/09/074148
CTRI/2024/09/074148已完成不适用

Assessment of periodontal health status in type 2 diabetes mellitus patients with glycemic levels.

DR SHAIK SHAZIA BEGUM1 个研究点 分布在 1 个国家目标入组 159 人开始时间: 2024年10月1日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
159
试验地点
1
主要终点
Assessing the periodontal health status using clinical and radiographic parameters in

研究概览

简要总结

The effect of diabetes on periodontium has been thoroughly investigated and confirmed as a major risk factor for periodontitis.On the other hand, periodontal disease may be a possible risk factor for poor glycemic control and promote the existence of diabetic complications.In patients with type 2 diabetes, severe periodontitis was associated with significant worsening of glycemic control over time.The high concentration of glucose in the fluid of gingival crevicular is due to the levels of glucose high in the plasma and it weakens the capacity of healing in fibroblasts of the periodontium, which is responsible for the health maintenance of the tissues.the gingival capillaries thickness increase in the patients having diabetes which possibly limit the diffusion of the nutrients and the oxygen supply and that causes the immune capacity to limited in the periodontal tissues.Various literature studies have assessed the correlation between diabetic patients and periodontal health through radiographical assessment and the efficiency of healing during periodontal interventions. But there still exists an ambiguity in the correlation between the glycemic levels of patients and its influence on the periodontal health. This prospective clinical study assesses the effect of blood glycemic levels as evaluated from HbA1c levels on the various clinical and radiographic parameters evaluating bone loss for periodontal status.

研究设计

研究类型
Observational

入排标准

年龄范围
35.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • 1.Subjects with history of diabetes past 2 years or more 2.Patients aged 35 to 60 years 3.Patients who are willing to participate in the study.

排除标准

  • 1.Subjects using any form of tobacco.
  • 2.Subjects with any other systemic diseases and medication 3.Subjects who underwent periodontal therapy past 1 year 4.Subjects with history of tooth loss due to trauma or dental caries or orthodontic extractions.
  • 5.Subjects who are under medication for Thiazolidinediones 6.Pregnant woman and Lactating mothers.

结局指标

主要结局

Assessing the periodontal health status using clinical and radiographic parameters in

时间窗: 3 months

patients with type 2 diabetes of varying glycemic levels

时间窗: 3 months

次要结局

  • Assessing the number of tooth lost in patients with type 2 diabetes of varying glycemic levels(3 months)

研究者

发起方
DR SHAIK SHAZIA BEGUM
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

SHAZIA BEGUM SHAIK

SIBAR INSTITUTE OF DENTAL SCIENCES

研究点 (1)

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