Performance of Surface Mechanomyography Using a Parasternal Patch to Measure and Detect Respiratory Drive and Effort in Healthy Volunteers - PATCH-MMG
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Accuracy of sMMG to detect respiratory effort
研究概览
简要总结
Surface mechanomyography (sMMG) has been proposed as a tool to study muscle mechanical activity. sMMG is a noninvasive technique using specific transducers to record muscle surface oscillations due to mechanical activity of the motor units . It could be of major interest for the detection of respiratory efforts in patients with respiratory failure. This study aims at assessing the performances of sMMG to measure and detect respiratory drive and effort in healthy volunteers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Crossover
- 主要目的
- Device Feasibility
- 盲法
- Single (Outcomes Assessor)
盲法说明
Recordings will be analysed by investigators blind to ventilation conditions
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy volunteer
- •Age > 18 and < 60
- •Informed consent
- •Subjects covered by or having the rights to medical care assurance
排除标准
- •Obesity (BMI > 30 kg.m-2)
- •Respiratory disease
- •Cardiovascular disease
- •Contraindication to the insertion of a nasogastric tube
- •Incapacity to consent
- •Pregnancy, breastfeeding
- •Bad understanding of the French language,
- •Other protected person according to articles L1121.7 and L1121.8 of the French Public Health Act.
结局指标
主要结局
Accuracy of sMMG to detect respiratory effort
时间窗: 5 minutes after the beginning of recording
Delays between the beginning of the respiratory effort detected by sMMG and Eadi and the end of the respiratory effort detected by sMMG and Eadi (msec)
次要结局
- Comparison between sMMG slope & Eadi parameters(5 minutes after the beginning of recording)
- Comparison between sMMG-time (MMG-TP) and PTPes-Pes Peak(5 minutes after the beginning of recording)
- Comparison between sMMG slope & slope Peso(5 minutes after the beginning of recording)
- Delay between neural time measured by sMMG and neural time measured by Eadi(5 minutes after the beginning of recording)