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临床试验/NCT01204346
NCT01204346Unknown不适用

Mentalization - Based Treatment for Young People Presenting With Co-morbid Depression and Symptoms of Emerging Personality Disorder: Prospective Controlled Trial.

North East London Foundation Trust2 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2010年12月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
75
试验地点
2
主要终点
Global assessment of functioning

研究概览

简要总结

Mentalisation based treatment (MBT) for young people with co-morbid depression and emerging personality disorder will be more effective in a day/inpatient setting than treatment as usual.

详细描述

Systematic literature review on outcomes with young people with depression and emerging personality disorder showed clear evidence that this group of young people are severely hampered and adult outcomes are strongly linked to both adult PD as well as adult psychiatric disturbance and lower levels of adult functioning. (Crawford et al, 2008; Kasen et al, 1999; Kasen et al, 2007; Lewinsohn et al, 1999) This argues very clearly for the need to diagnose young people presenting with co-morbid depression and emerging personality disorder in order to intervene and help these young people's struggles as it will prevent poor prognostic adult outcomes. There were no treatment programs that specifically focussed on the treatment of this co-morbid group in the literature. Several studies focussed on the treatment of depression alone and only one RCT focussed on the treatment of adolescent personality disorder (Chanen et al, 2007). In adult studies mentalization-based treatment programs were found to be effective ( as well as cost effective) in a day hospital setting for adults with personality disorder and depression (Bateman, et al, 2007) This study aims to conduct a control trial to test whether MBT will be more effective than TAU in this group. All cases will be tested on admission, at discharge and followed up at 2 years post discharge.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Investigator)

入排标准

年龄范围
12 Years 至 17 Years(Child)
性别
All
接受健康志愿者

入选标准

  • all young people who are admitted to Brookside adolescent unit between the ages 12 - 17 presenting with depression and emerging personality disorder will be eligible

排除标准

  • Young people with autistic spectrum disorders or severe learning disabilities.

结局指标

主要结局

Global assessment of functioning

时间窗: within 1 week of admission

measures level of functioning

global assessment of functioning

时间窗: Average of 8 weeks

measures level of functioning

次要结局

  • mood and feelings questionnaire(At average of 8 weeks)
  • Mood and feelings questionnaire(Within 1 week of admission)

研究者

发起方
North East London Foundation Trust
申办方类型
Other
责任方
Principal Investigator
主要研究者

Trudie Rossouw

Dr

North East London Foundation Trust

研究点 (2)

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