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Clinical Trials/NCT01204346
NCT01204346
Unknown
Not Applicable

Mentalization - Based Treatment for Young People Presenting With Co-morbid Depression and Symptoms of Emerging Personality Disorder: Prospective Controlled Trial.

North East London Foundation Trust1 site in 1 country75 target enrollmentDecember 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Depression
Sponsor
North East London Foundation Trust
Enrollment
75
Locations
1
Primary Endpoint
Global assessment of functioning
Last Updated
11 years ago

Overview

Brief Summary

Mentalisation based treatment (MBT) for young people with co-morbid depression and emerging personality disorder will be more effective in a day/inpatient setting than treatment as usual.

Detailed Description

Systematic literature review on outcomes with young people with depression and emerging personality disorder showed clear evidence that this group of young people are severely hampered and adult outcomes are strongly linked to both adult PD as well as adult psychiatric disturbance and lower levels of adult functioning. (Crawford et al, 2008; Kasen et al, 1999; Kasen et al, 2007; Lewinsohn et al, 1999) This argues very clearly for the need to diagnose young people presenting with co-morbid depression and emerging personality disorder in order to intervene and help these young people's struggles as it will prevent poor prognostic adult outcomes. There were no treatment programs that specifically focussed on the treatment of this co-morbid group in the literature. Several studies focussed on the treatment of depression alone and only one RCT focussed on the treatment of adolescent personality disorder (Chanen et al, 2007). In adult studies mentalization-based treatment programs were found to be effective ( as well as cost effective) in a day hospital setting for adults with personality disorder and depression (Bateman, et al, 2007) This study aims to conduct a control trial to test whether MBT will be more effective than TAU in this group. All cases will be tested on admission, at discharge and followed up at 2 years post discharge.

Registry
clinicaltrials.gov
Start Date
December 2010
End Date
December 2016
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
North East London Foundation Trust
Responsible Party
Principal Investigator
Principal Investigator

Trudie Rossouw

Dr

North East London Foundation Trust

Eligibility Criteria

Inclusion Criteria

  • all young people who are admitted to Brookside adolescent unit between the ages 12 - 17 presenting with depression and emerging personality disorder will be eligible

Exclusion Criteria

  • Young people with autistic spectrum disorders or severe learning disabilities.

Outcomes

Primary Outcomes

Global assessment of functioning

Time Frame: within 1 week of admission

measures level of functioning

global assessment of functioning

Time Frame: Average of 8 weeks

measures level of functioning

Secondary Outcomes

  • mood and feelings questionnaire(At average of 8 weeks)
  • Mood and feelings questionnaire(Within 1 week of admission)

Study Sites (1)

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