Comparing impact of coconut oil versus palm oil on selected cardiovascular disease risk factors in free-living healthy adults in households of a selected area in Colombo: single arm study

Not Applicable

Recruiting

Conditions: Cardiovascular disease risk

Registration Number: SLCTR/2019/034

Lead Sponsor: Prof. Ananda Jayawardane

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 40

Inclusion Criteria

1. Free living healthy adults who take their meals at home.
2. Both male and female between 18-60 years.

Exclusion Criteria

1. Those who have a medical history of cardiovascular diseases, stroke, thyroid disease, diabetes mellitus, liver or renal dysfunction (acute or chronic), peptic ulceration, cancer.
2. Those who smoke or consume alcohol.
3. Individuals taking any medications for dyslipidemia, hypercholesterolemia, or inflammatory disorders or patients receiving tetracycline therapy.
4. Those who use herbal/ antioxidant or vitamin or mineral/omega 3 or omega 6 supplements.
5. Those who follow weight loss regime, any prescribed diet or who frequently consume food from outside.
8. Pregnant and lactating mothers.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Difference in mean serum LDL-Cholesterol in the group between coconut feeding period and palm oil feeding period [Difference between baseline and end of 8 weeks of each feeding periods of both coconut and palm oil feedings.]<br>

Secondary Outcome Measures

Name	Time	Method
The change in mean of the following variables within the group before and after coconut and palm oil consumption.<br><br>i.Serumtotal and high-density lipoprotein cholesterol (Total Cholesterol and HDL-C), TC/HDL-C ratio, Triglycerides, VLDs, hs-CRP, fasting plasma glucose, glycated haemoglobin (HbA1c), Apo A, Apo B,), ALT and AST <br><br>ii.Weight, body mass index (BMI), waist circumference, waist to hip ratio, changes in body composition <br><br>iii.Systolic and diastolic blood pressure<br><br> [Difference between baseline and end of 8 weeks of each coconut and palm oil feeding periods.]<br>