Comparative evaluation of low dose hypobaric and hyperbaric bupivacaine for surgeries under unilateral spinal anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1.Efficacy of the Blockade
研究概览
简要总结
Hyperbaric bupivacaine is used for unilateral spinal anaesthesia .This is performed in lateral position and side to be operated to be down. Unilateral spinal anaesthesia with hypobaric bupivacaine is given with side to be operated upwards. this helps in making patient proper position and also there is no need of turning patient back for the start of surgery.So in this study we will compare low dose hypobaric and and hyperbaric bupivacaine for unilateral spinal anaesthesia in terms of efficacy of blockade, haemodynamic stability, anaesthesia onset and offset time and patient satisfaction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Sixty patients of either sex, ASA grade I-III, aged between 18-65 years posted for unilateral lower limb surgeries.
- •Procedures lasting for maximum duration of 60 minutes will be included.
排除标准
- •1.Hypovolemia, 2.Preexisting Neurological Disease, 3.Coagulation Disorders, 4.Administration of thromboprophylaxis less than eight hours prior to the surgery 5.Infection At The Puncture site, 6.Agitation And Delirium,.
结局指标
主要结局
1.Efficacy of the Blockade
时间窗: 1.Immediately after spinal anaesthesia | 2. At 15 min interval during surgery | 3.At the end of surgery
2.Haemodynamic Stability
时间窗: 1.Immediately after spinal anaesthesia | 2. At 15 min interval during surgery | 3.At the end of surgery
3.Anaesthesia onset and offset time,
时间窗: 1.Immediately after spinal anaesthesia | 2. At 15 min interval during surgery | 3.At the end of surgery
4.Patient satisfaction
时间窗: 1.Immediately after spinal anaesthesia | 2. At 15 min interval during surgery | 3.At the end of surgery
次要结局
- Side effects related to drugs ie Bradycardia(Hypotension)