Development and Evaluation of a Virtual Reality Application for Eliciting Craving and Its Physiological Arousal in Cocaine Users
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 11
- 试验地点
- 2
- 主要终点
- Cocaine Craving Intensity
研究概览
简要总结
Our study main objective is to test whether virtual reality exposure could elicit cocaine craving and its physiological arousal in cocaine users. Investigators aim to compare self-reported cocaine craving, self-efficacy to cope with craving and emotional states levels in 11 voluntary and adults cocaine users in 3 consecutive 10-mins conditions: Neutral VR (virtual reality exposure to neutral stimuli), Cocaine VR (virtual reality exposure to cocaine use-related stimuli) and Relaxation (respiratory relaxation).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •- Cocaine use within the past 28 days
排除标准
- •Actual manic or hypomanic episode (MINI, Lecrubier and al., 1998)
- •Actual psychotic episode (MINI, Lecrubier and al., 1998)
- •Actual high suicidal risk (MINI, Lecrubier and al., 1998)
- •Being involved in incarceration procedure
- •Medical risk for safety while physiological arousal (e.g. cardiac disease)
- •Disability for performing virtual reality task (e.g. blindness or deafness)
- •Significant motion sickness symptoms (SSQ pre-post total score ≥ 15, Bimberg et al., 2020)
结局指标
主要结局
Cocaine Craving Intensity
时间窗: Immediatly after Neutral VR, Cocaine VR and Relaxation (10 mins between each measure)
Change in self-reported cocaine craving intensity between 3 consecutive interventions: Neutral VR, Cocaine VR and Relaxation (CCQ-Brief total score, french version; Karila and al., 2011). CCQ-Brief total score varies from 10 to 70 (higher score suggesting higher craving intensity).
次要结局
- Negative Emotional States(Immediatly after Neutral VR, Cocaine VR and Relaxation (10 mins between each measure))
- Self-Efficacy to Cope with Cocaine Craving without Using(Immediatly after Neutral VR, Cocaine VR and Relaxation (10 mins between each measure))
- Positive Emotional States(Immediatly after Neutral VR, Cocaine VR and Relaxation (10 mins between each measure))
研究者
Thomas Lehoux
Ph.D. Candidate
Laboratoire de Psychologie des Cognitions