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Will Restasis Eye Drops Increase Your Chance of Having a Successful Surgery?

Not Applicable
Completed
Conditions
Glaucoma
Interventions
Registration Number
NCT00405431
Lead Sponsor
Wills Eye
Brief Summary

The purpose of this study is to determine whether reducing inflammation of the surface of the eye with topical Restasis after glaucoma surgery will improve surgical outcomes and increase patient comfort.

Detailed Description

Continued use of glaucoma drops can alter the outer surface of the eye and result in swelling and irritation, changing the structure of the eye. This structural change has been found to be a significant risk factor for the failure of glaucoma surgery. A comparison of how well patients do after glaucoma surgery depending on whether they use Restasis (the only prescription medication approved by the FDA for treating dry eye) or artificial tears (which can be purchased without a prescription) for 6 months following their surgery.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
43
Inclusion Criteria
  • Patients with uncontrolled glaucoma scheduled for filtering surgery
Exclusion Criteria
  • Under 18 years of age
  • Unable to understand informed consent

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
2Endura (artificial tears)Patients receive artificial tears (Endura) during 6 month post-operative period
1RestasisPatients received restasis eyedrops during 6 month post-operative period
Primary Outcome Measures
NameTimeMethod
intraocular pressure6 months
Secondary Outcome Measures
NameTimeMethod
ocular inflammation6 months

Trial Locations

Locations (1)

Wills Eye Glaucoma Service

🇺🇸

Philadelphia, Pennsylvania, United States

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