The Effect of Dietary Interventions, or no Intervention, on Pain and Quality of Life in Women Diagnosed With Endometriosis
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Endometriosis
- Sponsor
- Amsterdam UMC, location VUmc
- Enrollment
- 62
- Locations
- 1
- Primary Endpoint
- pain scores
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
This prospective pilot study was performed to explore the influence of a dietary intervention, the Low FODMAP diet or endometriosis diet, on endometriosis-related pain and Quality of Life (QoL). Participants could choose between adherence to a diet; the Low FODMAP diet or endometriosis diet, or to contribute to the control group and not adhere to a diet.
Detailed Description
This prospective pilot study was performed to explore the influence of a dietary intervention, the Low FODMAP diet or endometriosis diet, on endometriosis-related pain and Quality of Life (QoL). Participants could choose between adherence to a diet; the Low FODMAP diet or endometriosis diet, or to contribute to the control group and not adhere to a diet. Women choosing to adhere to a diet were extensively guided by a dietician in training. In addition, both groups are asked to complete three questionnaires over a period of six months; once every two months.
Investigators
Prof. Velja Mijatovic
Professor Doctor
Amsterdam UMC, location VUmc
Eligibility Criteria
Inclusion Criteria
- •Women diagnosed with endometriosis, either through radiologic imaging (transvaginal ultrasound and/or MRI) or laparoscopy
- •A reported pain score of ≥ 3 (Visual Analogue Score (VAS), scale 0-10cm) in one or more of the following symptoms: dysmenorrhea, deep dyspareunia and chronic pelvic pain
Exclusion Criteria
- •about to undergo an operation within six months
- •Undergone an operation in the past six weeks
- •a switch in hormonal therapy within six weeks
- •Women that were pregnant or breastfeeding
- •women diagnosed with a malignancy
- •An additional diagnosis with Coeliac Disease (CD) and/or lactose intolerance.
- •Not sufficient in the Dutch or English language.
Outcomes
Primary Outcomes
pain scores
Time Frame: 6 months
The primary outcome focused on pain scores (in VAS, scale 0-10cm) of the endometriosis-related symptoms dysmenorrhea, deep dyspareunia, chronic pelvic pain, dysuria, dyschezia, tiredness and bloating. Pain scores will be measured on a scale between 0 and 10, where 0 represents no pain at all and 10 the worst pain possible.
Secondary Outcomes
- Gastro-Intestinal Health(6 months)
- Adhesion to dietary intervention(6 months)
- Quality of Life (QoL)(6 months)