Klinische controle na een klep-sparende hartoperatie

• Conditions: outcome after valve sparing root replacement

• Registration Number: NL-OMON24825
• Lead Sponsor: Erasmus MC Rotterdam

Brief Summary

• Does pregnancy influence the durability of human aortic valve substitutes? Bardia Arabkhani, MSc, Helena J. Heuvelman, MD, MSc, Ad J.J.C. Bogers, MD, PhD, M. Mostafa Mokhles, MSc, Jolien W. Roos-Hesselink, MD, PhD, Johanna J.M. Takkenberg, MD, PhD. J Am Coll Cardiol. 2012;60(19):1991-1992. doi:10.1016/j.jacc.2012.06.055 <br><br> • Outcome of Pregnancy in Women who received a Human or Mechanical Aortic Valve Substitute. H.J. Heuvelman, MD, B. Arabkhani, P.G. Pieper, MD, PhD, J.J.M. Takkenberg, MD, PhD, J.M.J. Cornette, A.J.J.C. Bogers , MD, PhD, J.W Roos-Hesselink, MD, PhD. Am J Cardiol. 2012 Nov 20. doi:pii: S0002-9149(12)02293-X. 10.1016/j.amjcard.2012.09.035. <br><br> • Therapeutic decisions for patients with symptomatic severe aortic stenosis: room for improvement? van Geldorp MW, van Gameren M, Kappetein AP, Arabkhani B, de Groot-de Laat LE, Takkenberg JJ, Bogers AJ. Eur J Cardiothorac Surg. 2009 Jun;35(6):953-7; discussion 957. Epub 2009 Mar 20.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

•All patients aged 18 years or older who received a valve sparing root reimplantation (Tirone David) at the Erasmus MC since 2000, not reoperated on the aortic valve
Signed informed consent by the patient and the investigator.

Exclusion Criteria

Patients who are unable to give informed consent.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Freedom of reoperation, survival and quality of life.

Secondary Outcome Measures

Name	Time	Method
Valve related complications.