Continued Early Intervention for Recent-onset Schizophrenia

Phase 3

Terminated

• Conditions: Schizophrenia

• Registration Number: NCT00184509
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

The purpose of this study was to determine whether outreach integrated treatment of first episode schizophrenia was more effecive than standard outpatient treatment.

Detailed Description

Early intervention for schizophrenia has spawned considerable enthusiasm among clinicians without solid research evidence to suport its benefits and costs. The present study is a random-controlled study of integrated biomedical and psychosocial treatment on a population of recent-onset cases.

Comparison(s): 50 consecutive referrals with schizophrenic disorders of less than two years duration were allocated randomly to a comprehensive model of integrated treatment or standard care for two years. Main outcome measures was psychopathology, psychosocial functioning and hospital admissions.

Study Timeline

• Study Start: 1993-02
• Study Completion: 1998-05
• Study First Submitted: 2005-09-15
• Study First Submitted QC: 2005-09-15
• Study First Posted: 2005-09-16
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-25
• Last Update Posted: 2017-01-26

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• first-episode schizophrenia

Exclusion Criteria

• acute psychosis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Rehospitalizations and psychotic relapse at two years

Secondary Outcome Measures

Name	Time	Method
Psychopathology, psychosocial changes, functioning, antipsychotic medication

Trial Locations

Locations (1)

Norwegian University of Science and Technology; 🇳🇴 Trondheim, Norway