NCT00350038已完成4 期
Investigations of the Effects of Aprovel, Lipanor and Their Combination Onto the Endothelial Functions of Dyslipidemic Patients Measure by Laser Doppler Flow-Metry.
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- Sanofi
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Microvascular reactivity
研究概览
简要总结
The rationale of the study is to clarify whether the supplementation of irbesartan with ciprofibrate could increase the antihypertensive effect, could improve the endothelial functions, and/or could affect the atherogenic small-dense LDL-, oxydized LDL concentrations, onto the paraoxinase activity and on the CRP and insulin levels.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •hypertensive + dyslipidemic + damaged endothelial function
排除标准
- •hepatic and kidney damage,
- •IDDM (Insulin Dependent Diabetes Mellitus)
- •Freckson V type hyperlipoproteinaemia
- •The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.
结局指标
主要结局
Microvascular reactivity
次要结局
- Reach of target blood pressure
- Measurements of safety laboratory parameters
研究者
研究点 (1)
Loading locations...
相似试验
已完成
3 期
Efficacy and Safety of Irbesartan and Atorvastatin in Hypertension and HyperlipidemiaHypertensionHyperlipidemiaNCT01442987Hanmi Pharmaceutical Company Limited230
已完成
2 期
Ciprofloxacin BioThrax Co-Administration StudyAnthraxNCT01753115Emergent BioSolutions154
已完成
1 期
Pharmacokinetics of Apricitabine and Tipranavir When Dosed Alone or TogetherHIV InfectionNCT00352066Avexa18
终止
1 期
Abiraterone Acetate in Combination With TildrakizumabMetastatic Castration Resistant Prostate CancerNCT04458311Institute of Cancer Research, United Kingdom13
进行中（未招募）
1 期
Combining Ipilimumab With Abiraterone Acetate Plus Prednisone in Chemotherapy and Immunotherapy-naïve Patients With Progressive Metastatic Castration-resistant Prostate CancerProstate CancerNCT01688492Memorial Sloan Kettering Cancer Center54