Comparing the clinical response of obsessive-compulsive patients refractory to serotonin reuptake inhibitor regimen with and without lamotrigine; a double-blind placebo controlled study
Phase 2
- Conditions
- Obsessive-compulsive patients.The essential feature is recurrent obsessional thoughts or compulsive acts.
- Registration Number
- IRCT2014031717045N1
- Lead Sponsor
- Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
OCD diagnosis on axis I based on DSM IV TR; Ages between 16 and 60; Yale Brown Obsessive Compulsive Score of more than 21
Exclusion criteria: Active psychotic disorder such as schizophrenia, psychotic bipolar disorder and major depressive disorder; Major organic disorder; Organic brain disorder; Drug and substance abuse; Mental retardation; Pregnancy and lactation; During psychotherapy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical response is measured by Yale Brown Obsessive Compulsive Scale. Timepoint: The day 0, 60 and 90. Method of measurement: Yale Brown Obsessive Compulsive Scale.
- Secondary Outcome Measures
Name Time Method