Can we reduce asthma attacks in children using spirometry measurements and symptoms?

Not Applicable

• Conditions: Asthma; Respiratory

• Registration Number: ISRCTN31849868
• Lead Sponsor: niversity of Aberdeen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-01
• Last Update Posted: 26 August 2024
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 550

Inclusion Criteria

1. Aged 6 to 15 years old
2. Asthma diagnosis confirmed by a doctor or a respiratory/asthma specialist nurse (or Read code for asthma if recruited in primary care)
3. Patient/parent reported-asthma attack treated with at least one course of oral corticosteroids in the 12 months prior to recruitment
4. Be able to perform spirometry
5. Be able to understand written/spoken English

Exclusion Criteria

1. Not being able to perform spirometry satisfactorily
2. Presence of another chronic respiratory condition (e.g. cystic fibrosis)
3. Current treatment with maintenance oral steroids and biologicals (we cannot provide standardised step-up/down treatment options)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Asthma attacks in children with spirometry plus asthma control (symptoms) compared with asthma control (symptoms) alone measured using participant-reported asthma attacks that require treatment with 1-7 days of oral corticosteroids and/or intravenous corticosteroids up to 12 months post-randomisation