RBR-38jcm9招募中未知
Pharmacokinetic/pharmacodynamic (PK/PD) model on the influence of P450 (CYP2C9) genetic polymorphism of non-steroidal anti-inflammatory drugs and major metabolites from saliva samples by LC MS/MS and their role in prescribing personalization
Faculdade de Odontologia de Bauru0 个研究点开始时间: 2020年2月19日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Intervention
入排标准
- 年龄范围
- 18Y 至 60Y（—）
入选标准
- •Good general health condition; absence of infection and inflammation; absence of systemic diseases; do not use any medicine that may alter the perception of pain or antidepressant, diuretic or anticoagulant medicines.
排除标准
- •Patients with systemic diseases; patients with inflammation or infection; patients with a history of gastrointestinal bleeding or ulcerations; patients with cardiovascular, renal or liver disease; patients taking antidepressant, diuretic or anticoagulant medications; patients with a history of allergy to any other NSAIDs; pregnant and lactating women.
研究者
相似试验
已完成
不适用
Population pharmacokinetic-pharmacodynamic model of general anesthesia for propofol, sufentanil and atracurium, considering the propofol exhaled air concentration and EEG (BIS)DRKS00017026niversitätsklinikum des Saarlandes35
已完成
1 期
Pharmacokinetic/Pharmacodynamic (PK/PD) Study to Evaluate Adrenaline (Epinephrine) Exposure Following Intramuscular Administration of Fastjekt® Auto-Injector (0.3 mg; Mylan) in Adult Volunteers with Varying Skin to Muscle Distance (STMD) in the Thighhealthy volunteersDRKS00011263Mylan Pharmaceuticals Inc.35
已完成
4 期
A relationship between pharmacokinetics (PK) and the efficacy of infliximab for patients with psoriasispsoriasisJPRN-UMIN000005310Department of Dermatology, Kawasaki Medical School10
已完成
不适用
Pharmacokinetic and pharmacodynamic modelling of routinely used off label drugs in premature neonates10039911Pijn en sedatiePrematurity10028971NL-OMON44214Erasmus MC, Universitair Medisch Centrum Rotterdam600
已完成
1 期
A single injection dose study of DUR-928 in patients with impaired kidney function and healthy volunteersImpaired Kidney Function – stage 3 and 4Renal and Urogenital - Kidney diseaseACTRN12616000389404George Clinical Pty Ltd18