To compare the effect of pain relief between two drugs in patients undergoing surgeries on the upper limb

Not yet recruiting

• Conditions: Fracture of shaft of ulna, (2) ICD-10 Condition: S518||Open wound of forearm,

• Registration Number: CTRI/2021/07/035211
• Lead Sponsor: Karnataka institute of medical sciences

Brief Summary

Levobupivacaine the pure S(-) enantiomer of racemic bupivacaine, is a new long acting local anaesthetic that has recently been introduced in the clinical routine. Because of its significantly decreased cardiovascular and central nervous system toxicity, levobupivacaine seems to be an attractive alternative to bupivacaine. It has become a popular practice to add opioids to local anaesthetic solutions to enhance and prolong intraoperative and postoperative analgesia. However lack of comparative studies and adequate information on the anaesthetic potency of levobupivacaine with an opioid prompted us to investigate the anaesthetic potency and hemodynamic effects of bupivacaine with buprenorphine compared with levobupivacaine with buprenorphine in patients undergoing upper limb surgeries in a prospective randomized double blinded study

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-08
• Last Update Posted: 2021-07-26

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Patients aged between 18-60 yrs with ASA physical status I–II who are scheduled for elective upper limb surgeries under brachial plexus block.

Exclusion Criteria

• 1.Known hypersensitivity to amide local anesthetics 2.
• Morbid obesity (150% the ideal weight or >130 kg).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
onset of sensory blockade with levobupivacaine faster than bupivacaine	checked at baseline and then every 5 minutes for 30 minutes

Secondary Outcome Measures

Name	Time	Method
Better hemodynamic stability in levobupivacaine group	Blood pressure and pulse rate checked at base line and every 5 minutes for 2 hours

Trial Locations

Locations (1)

Karnataka institute of medical sciences; 🇮🇳 Dharwad, KARNATAKA, India

Karnataka institute of medical sciences

🇮🇳Dharwad, KARNATAKA, India

Dr Pushpavathi Ture

Principal investigator

9448251597

pushpadrture@rediffmail.com