NCT00394537已完成4 期
Labetalol to Prevent Hypertension and Tachycardia During Fiberoptic Bronchoscopy
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 2
- 主要终点
- Heart Rate
研究概览
简要总结
Passing a bronchoscope through the airways frequently causes a stress response even though patients are sedated. This stress response is usually an increase in pulse and blood pressure, which may have undesirable effects on the heart and circulation.
We plan to give patients labetalol (a beta blocker which reduces pulse and blood pressure) in addition to normal sedation, to patients undergoing bronchoscopy in our department.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients over 18 years old undergo fiberoptic bronchoscopy in our unit
排除标准
- •inability or refusal to give informed consent
- •bronchoscopy through an artificial airway
- •intolerance or allergy to the study drug
- •bradycardia (HR<60/min) or hypotension (systolic BP <100) at screening
- •pregnancy,
- •concomitant treatment with diltiazem or verapamil
- •intention to use propofol as the sedative agent for bronchoscopy.
结局指标
主要结局
Heart Rate
Systolic Blood Pressure
Diastolic Blood Pressure
Rate pressure product (HR*SBP/100)
次要结局
未报告次要终点
研究者
研究点 (2)
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