Clinical study to evaluate the effect of 2% lignocaine injection with alkalinized 2% lignocaine injection for tooth removal
Phase 2/3
Completed
- Conditions
- Injection pain and anesthetic latency in those requiring dental extractions
- Registration Number
- CTRI/2018/06/014559
- Lead Sponsor
- G Bharatiram
- Brief Summary
The purpose of the study is to compare theanesthetic latency and injection pain for Buffered Local Anesthesia versus NonBuffered Local Anesthesia. In this double-blind, placebo-controlled, cross overinvestigation, 25 patients those requiring bilateral dental extractions underlocal anesthesia are selected. The sides of patients were randomized toBuffered Local Anesthesia or Non Buffered Local Anesthesia group. Evaluation ofpain on injection (carried out with the use of a 5- point Likert scale) and anestheticlatency (time of onset) are carried out.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- Healthy participants those requiring bilateral dental extractions 2.
- Patients in the age group of 18- 50 years.
Exclusion Criteria
- Patients with debilitating systemic diseases 2.
- Patients with renal and cardiac problems 3.
- Pregnant women 4.
- Patients having abscess, cyst, space infections associated with teeth to be extracted.
- Subjects who had analgesic or anti inflammatory drugs 24 hours before treatment 6.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain on injection with 5 point Likert Scale 3-120 seconds on injection
- Secondary Outcome Measures
Name Time Method Anesthetic latency (time of onset)
Trial Locations
- Locations (1)
Vishnu Dental College
🇮🇳Godavari, ANDHRA PRADESH, India
Vishnu Dental College🇮🇳Godavari, ANDHRA PRADESH, IndiaKishore MoturiPrincipal investigator9849094159moturik@gmail.com